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953805-24-8

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  • (3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(2-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)ethyl)azetidin-2-one,953805-24-8

    Cas No: 953805-24-8

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  • Henan Tianfu Chemical Co., Ltd.
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953805-24-8 Usage

Description

(3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(2-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)ethyl)azetidin-2-one is a complex synthetic compound with a unique azetidin-2-one core structure, featuring substituted phenyl and benzyl groups, as well as fluorophenyl and 5,5-diMethyl-1,3-dioxan-2-yl moieties. Its intricate molecular architecture suggests potential applications in pharmaceutical research, warranting further investigation into its properties and possible uses.

Uses

Used in Pharmaceutical Research:
(3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(2-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)ethyl)azetidin-2-one is used as a potential candidate in pharmaceutical research for its unique molecular structure and possible biological activity. (3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(2-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)ethyl)azetidin-2-one's intricate design may offer novel therapeutic opportunities, pending further study and analysis.
Used in Drug Development:
In the drug development industry, (3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(2-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)ethyl)azetidin-2-one is used as a starting point for the design and synthesis of new drugs. Its distinct structural features may lead to the creation of innovative medications with improved efficacy and reduced side effects.
Used in Chemical Synthesis:
(3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(2-(2-(4-fluorophenyl)-5,5-diMethyl-1,3-dioxan-2-yl)ethyl)azetidin-2-one serves as a versatile building block in chemical synthesis, allowing for the creation of a variety of new compounds with diverse applications across different industries.
Please note that the specific applications and industries for this compound are speculative, as the provided materials do not detail its exact uses. Further research and development would be necessary to determine its full potential in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 953805-24-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,3,8,0 and 5 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 953805-24:
(8*9)+(7*5)+(6*3)+(5*8)+(4*0)+(3*5)+(2*2)+(1*4)=188
188 % 10 = 8
So 953805-24-8 is a valid CAS Registry Number.

953805-24-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R,4S)-4-(4-benzyloxyphenyl)-1-(4-fluorophenyl)-3-{2-[2-(4-fluorophenyl)-5,5-dimethyl-[1,3]dioxan-2-yl]-ethyl}azetidin-2-one

1.2 Other means of identification

Product number -
Other names 4(S)-(4-benzyloxyphenyl)-1-(4-fluorophenyl)-3(R)-{2-[2-(4-fluorophenyI)-5,5-dimethyl-[1,3]-dioxan-2-yl]-ethyl}azetidine-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:953805-24-8 SDS

953805-24-8Relevant articles and documents

Ezetimibe intermediate, synthesis method of intermediate and synthesis method of ezetimibe

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, (2017/07/01)

The invention provides an ezetimibe intermediate, a synthesis method of the intermediate and a synthesis method of ezetimibe. The method is short in synthetic route. The method includes the steps of making fluorobenzene as the initial raw material sequentially have acylation reaction with glutaric anhydride and 4(S)-4-phenyl oxazolidinone to generate a compound II, protecting carbonyl through 2,2-bis-substituted-1,3-propylene glycol to obtain a compound III, generating a compound V through the compound III and a compound IV under the catalysis of titanium tetrachloride, cyclizing the compound V to generate a compound VI, hydrolyzing the compound VI to obtain a compound VII, and reducing the compound VII through a borane chiral reducing agent and removing a benzyl protecting group in a hydrogenated mode to obtain the ezetimibe. The method is high in yield, little in side reaction and suitable for industrial mass production.

PROCESSES FOR THE SYNTHESIS OF AZETIDINONE

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Page/Page column 62-63, (2008/06/13)

Provided are intermediates useful for the synthesis of hydroxyl-alkyl substituted azetidinones, processes of their preparation, and processes for the synthesis of certain hydroxyl-alkyl substituted azetidinones. Also provided are processes for the synthesis ofl-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)- hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, or ezetimibe.

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