95407-00-4Relevant articles and documents
Synthesis and activity of pyrimidinylpropenamide antibiotics: The alkyl analogues of sparsomycin
Nakajima, Noriyuki,Enomoto, Takeshi,Watanabe, Takehiro,Matsuura, Nobuyasu,Ubukata, Makoto
, p. 2556 - 2566 (2007/10/03)
Facile syntheses of sparsomycin (3) and its four analogues (4-7) based on diastereoselective oxidation of sulfide, sulfenylation, and coupling of 6-methyluracylacryllic acid with monooxodithioacetal amine, are described. Studies on the biological activity of morphological reversion on src ts-NRK cells were also carried out.