95503-20-1

Basic information

• Product Name: 1H-Indole, 1,1'-[oxybis(methylene)]bis[3-phenyl-
• CAS NO: 95503-20-1
• Molecular Formula: C30H24N2O
• Molecular Weight: 428.533
• Mol File: 95503-20-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 1,1'-[oxybis(methylene)]bis[3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 1,1'-[oxybis(methylene)]bis[3-phenyl-(95503-20-1)
• EPA Substance Registry System: 1H-Indole, 1,1'-[oxybis(methylene)]bis[3-phenyl-(95503-20-1)

Safety Data

• Hazardous Substances Data: 95503-20-1(Hazardous Substances Data)

Upstream product

• 83824-09-3 3-phenylindole-1-carboxaldehyde 

Relevant articles and documents

DIBORANE AS A REDUCING AGENT - VI. THE NOVEL REDUCTION OF INDOLE-1-CARBOXALDEHYDES TO 1-METHYL-INDOLES, DI(INDOLYLMETHYL)ETHERS AND INDOLYLMETHYL INDOLINES

Reduction of the indole-1-carboxaldehydes (1a-1f) with borane/THF gives the 1-methylindoles (4) in 42-91 percent yields together with the di(indolylmethyl)ethers (8), the indolylmethyl indolines (7), the unsymmetric ether (10) and the indolenine (11) as the minor products, except 7a.This appears to be the first report on the formation of symmetric ethers in the borane/THF reduction of an oxygen function.The formation of 7a and 7b from 1a and 1b implies that electrophilic substitution takes place primarily at position 3 of 3-substituted indoles. 1c-1f did not form the corresponding 7 probably because of steric hindrance.These results are discussed in relation to the mechanisms of borane/THF reduction, origin of the different products and electrophilic substitution in 3-substituted indoles.