95519-32-7

Basic information

• Product Name: benzhydryl (2R,4S)-2-<(1R)-2-hydroxy-1-phenoxyacetylaminoethyl>-5,5-dimethylthiazolidine-4-carboxylate
• CAS NO: 95519-32-7
• Molecular Weight: 520.649
• Mol File: 95519-32-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzhydryl (2R,4S)-2-<(1R)-2-hydroxy-1-phenoxyacetylaminoethyl>-5,5-dimethylthiazolidine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzhydryl (2R,4S)-2-<(1R)-2-hydroxy-1-phenoxyacetylaminoethyl>-5,5-dimethylthiazolidine-4-carboxylate(95519-32-7)
• EPA Substance Registry System: benzhydryl (2R,4S)-2-<(1R)-2-hydroxy-1-phenoxyacetylaminoethyl>-5,5-dimethylthiazolidine-4-carboxylate(95519-32-7)

Safety Data

• Hazardous Substances Data: 95519-32-7(Hazardous Substances Data)

Upstream product

• 52141-84-1 (2S,5R,6R)-benzhydryl 6-(2-phenoxyacetamido)-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate 

Downstream Products

• 95519-33-8 benzhydryl (2R,4S)-2-<(1R)-2-acetoxy-1-phenoxyacetylaminoethyl>-5,5-dimethylthiazolidine-4-carboxylate 

Relevant articles and documents

Diborane Reduction of Penicillins: Preparation of 7-Deoxopenicillanic Acid

The reduction of 6β-acylamidopenicillanates with diborane is shown to proceed by opening of the β-lactam ring to produce the corresponding amino alcohols.The chemistry of the reduction product from benzhydryl 6β-benzyloxycarbonylaminopenicillanate has been explored, in paticular its reaction with methanolic potassium hydroxide; no azetidines are formed.Cyclisation of the amino alcohol prepared from methyl penicillanate may be effected either indirectly, via the corresponding bromide, or directly, by use of a modified Mitsunobu reaction, to produce methyl 7-deoxypenicillanate.