95526-07-1Relevant articles and documents
Switching on a signaling pathway with an organoruthenium complex
Williams, Douglas S.,Atilla, G. Ekin,Bregman, Howard,Arzoumanian, Arpine,Klein, Peter S.,Meggers, Eric
, p. 1984 - 1987 (2005)
Like an organic molecule! A chemically inert ruthenium complex acts as a metallopharmaceutic inhibitor of the protein kinase GSK-3 by targeting its ATP-binding site. It is shown to switch on the Wnt signal transduction pathway inside living cells and in X