955369-50-3

Basic information

• Product Name: tert-butyl 4-(4-amino-2-methylphenyl)-piperidine-1-carboxylate
• Synonyms: tert-butyl 4-(4-amino-2-methylphenyl)-piperidine-1-carboxylate
• CAS NO: 955369-50-3
• Molecular Weight: 290.406
• Mol File: 955369-50-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(4-amino-2-methylphenyl)-piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(4-amino-2-methylphenyl)-piperidine-1-carboxylate(955369-50-3)
• EPA Substance Registry System: tert-butyl 4-(4-amino-2-methylphenyl)-piperidine-1-carboxylate(955369-50-3)

Safety Data

• Hazardous Substances Data: 955369-50-3(Hazardous Substances Data)

Upstream product

• 955369-49-0 tert-butyl 4-(4-amino-2-methyl-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylate 
• 7149-70-4 2-bromo-5-nitrotoluene 
• 1232785-32-8 tert-butyl 4-(2-methyl-4-nitrophenyl)-5,6-dihydropyridine-1(2H)-carboxylate 
• 375853-82-0 tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate 
• 844501-00-4 tert-butyl 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylate 
• 6933-10-4 amino-5-bromo-2-toluene 

Downstream Products

• 1176104-20-3 3-methyl-4-(1-methylpiperidin-4-yl)aniline 
• 1175553-61-3 6-(6-methoxypyrazin-2-yl)-8-{[3-methyl-4-(piperidin-4-yl)phenyl]amino}-1,2-dihydro-2,7-naphthyridin-1-one 
• 1263400-45-8 tert-butyl 4-(4-(3-chloro-8-oxo-7-((2-(trimethylsilyl)ethoxy)methyl)-7,8-dihydro-2,7-naphthyridin-1-ylamino)-2-methylphenyl)piperidine-1-carboxylate 
• 1263400-46-9 tert-butyl 4-(4-(3-(6-methoxypyrazin-2-yl)-8-oxo-7-((2-(trimethylsilyl)ethoxy)methyl)-7,8-dihydro-2,7-naphthyridin-1-ylamino)-2-methylphenyl)piperidine-1-carboxylate 
• 1263390-26-6 3-(4-(4-(3-(6-methoxypyrazin-2-yl)-8-oxo-7,8-dihydro-2,7-naphthyridin-1-ylamino)-2-methylphenyl)piperidin-1-yl)propanenitrile 
• 1263400-43-6 tert-butyl 4-(4-(3-(6-methoxypyrazin-2-yl)-8-oxo-7,8-dihydro-2,7-naphthyridin-1-ylamino)-2-methylphenyl)piperidine-1-carboxylate 
• 1263400-42-5 tert-butyl 4-(4-(3-chloro-8-oxo-7,8-dihydro-2,7-naphthyridin-1-ylamino)-2-methylphenyl)piperidine-1-carboxylate 
• 1566584-62-0 tert-butyl 4-(4-((4-((2-(2-methoxy-2-oxoethyl)phenyl)ethynyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-2-methylphenyl)piperidine-1-carboxylate 
• 1566584-63-1 tert-butyl 4-(4-((4-(2-(2-methoxy-2-oxoethyl)phenethyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-2-methylphenyl)piperidine-1-carboxylate 
• 1566584-64-2 tert-butyl 4-(4-((4-(2-(2-amino-2-oxoethyl)phenethyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-2-methylphenyl)piperidine-1-carboxylate 
• 1566583-93-4 2-(2-(2-(2-((3-methyl-4-(piperidin-4-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)phenyl)acetamide 
• 1566583-94-5 2-(2-(2-(2-((3-methyl-4-(1-methylpiperidin-4-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)phenyl)acetamide 
• 1383682-55-0 tert-butyl 4-(4-((4-chloro-5-(trifluoromethyl)pyrimidine-2-yl)amino)-2-methylphenyl)piperidine-1-carboxylate 

Relevant articles and documents

OXO-TETRAHYDRO-ISOQUINOLINE CARBOXYLIC ACIDS AS STING INHIBITORS

The instant invention provides compounds of formula I which are STING inhibitors, and as such are useful for the treatment of STING-mediated diseases such as inflammation, asthma, COPD and cancer.

WEE-1 INHIBITING PYRIDOPYRIMIDINONE COMPOUNDS

The present invention relates to compounds that are useful as inhibitors of the activity of Wee-1 kinase. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.

TANK-BINDING KINASE INHIBITOR COMPOUNDS

Compounds having the following formula (I) and methods of their use and preparation are disclosed: