955369-59-2Relevant articles and documents
Internal Nucleophilic Catalyst Mediated Cyclisation/Ring Expansion Cascades for the Synthesis of Medium-Sized Lactones and Lactams
Lawer, Aggie,Rossi-Ashton, James A.,Stephens, Thomas C.,Challis, Bradley J.,Epton, Ryan G.,Lynam, Jason M.,Unsworth, William P.
supporting information, p. 13942 - 13947 (2019/08/28)
A strategy for the synthesis of medium-sized lactones and lactams from linear precursors is described in which an amine acts as an internal nucleophilic catalyst to facilitate a novel cyclisation/ring expansion cascade sequence. This method obviates the n