956010-25-6

Basic information

• Product Name: Methyl 1-benzyl-4-hydroxypiperidine-3-carboxylate
• Synonyms: 4-Hydroxy-1-(phenylmethyl)-3-piperidinecarboxylic acid ethyl ester;3-Piperidinecarboxylic acid, 4-hydroxy-1-(phenylMethyl)-, ethyl ester;ethyl 1-benzyl-4-hydroxypiperidine-3-carboxylate;Methyl 1-benzyl-4-hydroxypiperidine-3-carboxylate
• CAS NO: 956010-25-6
• Molecular Formula: C₁₅H₂₁NO₃
• Molecular Weight: 249.30556
• Mol File: 956010-25-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.160
• CAS DataBase Reference: Methyl 1-benzyl-4-hydroxypiperidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 1-benzyl-4-hydroxypiperidine-3-carboxylate(956010-25-6)
• EPA Substance Registry System: Methyl 1-benzyl-4-hydroxypiperidine-3-carboxylate(956010-25-6)

Safety Data

• Hazardous Substances Data: 956010-25-6(Hazardous Substances Data)

Usage

General Description

Methyl 1-benzyl-4-hydroxypiperidine-3-carboxylate is a chemical compound that belongs to the class of piperidine derivatives. It is a methyl ester of 1-benzyl-4-hydroxypiperidine-3-carboxylic acid and is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and medications. Methyl 1-benzyl-4-hydroxypiperidine-3-carboxylate has potential medicinal properties and may have a role in the treatment of central nervous system disorders such as depression and anxiety. Its precise physiological and pharmacological effects are still under investigation, and further research is needed to fully understand its potential applications.

InChI:InChI=1S/C15H21NO3/c1-2-19-15(18)13-11-16(9-8-14(13)17)10-12-6-4-3-5-7-12/h3-7,13-14,17H,2,8-11H2,1H3

Upstream product

• 41276-30-6 C₉H₁₄O₃NC₆H₅ 
• 1454-53-1 ethyl 1-benzyl-4-oxopiperidine-3-carboxylate hydrochloride 

Downstream Products

• 886-46-4 (3RS,4RS)-1-benzyl-3-hydroxymethyl-piperidin-4-ol 

Relevant articles and documents

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES

The present invention discloses compounds according to Formula I: wherein R1, R2a, X, Y, and Z are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising th

2,4-Dioxa-7-aza-, 2,4-dioxa-8-aza-, and 2,4-dioxa-9-aza-3-phosphadecalins as rigid acetylcholine mimetics: Syntheses and characterization

Phosphorylation of suitable piperidine precursors yielded a series of novel decalin-type O,N,P-heterocycles. The title compounds, P(3)-axially and P(3)-equatorially X-substituted, cis- and trans-configurated 2,4-dioxa-7-aza-, 2,4-dioxa-8-aza-, and 2,4-dioxa-9-aza-3-phosphabicyclo[4.4.0]decane 3-oxides (X = Cl, F, 4-nitrophenoxy, and 2,4-dinitrophenoxy), are configuratively fixed and conformationally constrained P-analogues of acetylcholine and as such represent acetylcholine (7-aza and 9-aza isomers) or γ-homo-acetylcholine mimetics (8-aza isomers). Being irreversible inhibitors of acetylcholinesterase (AChE), the compounds are considered to be suitable probes for the investigation of the stereochemical course of the inhibition reaction by 31P-NMR spectroscopy. Moreover, the design of these mimetics will enable studies of molecular interactions with AChE, in particular, the recognition conformation of acetylcholine.