956293-17-7

Basic information

• Product Name: pyrrolo[2,1-b]thiazole-7-carboxylic acid ethyl ester
• CAS NO: 956293-17-7
• Molecular Weight: 195.242
• Mol File: 956293-17-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: pyrrolo[2,1-b]thiazole-7-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: pyrrolo[2,1-b]thiazole-7-carboxylic acid ethyl ester(956293-17-7)
• EPA Substance Registry System: pyrrolo[2,1-b]thiazole-7-carboxylic acid ethyl ester(956293-17-7)

Safety Data

• Hazardous Substances Data: 956293-17-7(Hazardous Substances Data)

Upstream product

• 5053-24-7 2-methylthio-1,3-thiazole 
• 623-47-2 propynoic acid ethyl ester 
• 64035-64-9 Trimethylsilylmethyl trifluoromethanesulfonate 

Relevant articles and documents

TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES

The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

Cycloaddition reactions of thiazolium azomethine ylides: Application to pyrrolo[2,1-b]thiazoles

Thiazolium azomethine ylides, equipped with a C-2 methanethiol group, participate in an efficient [3 + 2] cycloaddition reaction with acetylene derivatives to yield unique pyrrolo[2,1-b]thiazoles. The elimination of the methanethiol leaving group from the cycloadduct has replaced the need for a separate oxidation step and suppresses ring-opening side reactions. Products were obtained in short synthetic sequences to demonstrate their use as a scaffold for compound libraries.