956722-57-9 Usage
Description
1-[1-(2-Methoxyethyl)piperidin-4-yl]methanamine, also known as 4-(2-methoxyethyl)-N-(piperidin-4-yl)methanamine, is a chemical compound that features a piperidine ring and a methoxyethyl side chain. It is structurally related to compounds with known pharmacological activity, particularly in the central nervous system. This makes it a promising candidate for pharmaceutical research and drug development, with potential applications in the treatment of neurological and psychiatric disorders.
Uses
Used in Pharmaceutical Research and Development:
1-[1-(2-Methoxyethyl)piperidin-4-yl]methanamine is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and potential pharmacological activity make it a valuable asset in the development of new drugs targeting the central nervous system.
Used in Neurological and Psychiatric Disorders:
1-[1-(2-Methoxyethyl)piperidin-4-yl]methanamine is used as a potential therapeutic agent for the treatment of neurological and psychiatric disorders. Its structural similarity to compounds with known pharmacological activity suggests that it may have beneficial effects on the central nervous system, offering new treatment options for patients suffering from these conditions.
Used in Drug Delivery Systems:
In the pharmaceutical industry, 1-[1-(2-Methoxyethyl)piperidin-4-yl]methanamine can be used as a component in drug delivery systems. Its chemical properties may allow for the development of innovative drug formulations that improve the bioavailability, efficacy, and safety of medications targeting the central nervous system.
Used in Chemical Synthesis:
1-[1-(2-Methoxyethyl)piperidin-4-yl]methanamine can be used as a building block in the synthesis of a wide range of organic compounds. Its versatile structure makes it a valuable precursor for the creation of new molecules with potential applications in various fields, including materials science, agrochemicals, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 956722-57-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,6,7,2 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 956722-57:
(8*9)+(7*5)+(6*6)+(5*7)+(4*2)+(3*2)+(2*5)+(1*7)=209
209 % 10 = 9
So 956722-57-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H20N2O/c1-12-7-6-11-4-2-9(8-10)3-5-11/h9H,2-8,10H2,1H3
956722-57-9Relevant articles and documents
Piperazine-and piperidine-containing thiazolo[5,4-d]pyrimidine derivatives as new potent and selective adenosine a2a receptor inverse agonists
Varano, Flavia,Catarzi, Daniela,Vigiani, Erica,Vincenzi, Fabrizio,Pasquini, Silvia,Varani, Katia,Colotta, Vittoria
, p. 1 - 19 (2020/07/31)
The therapeutic use of A2A adenosine receptor (AR) antagonists for the treatment of neurodegenerative disorders, such as Parkinson and Alzheimer diseases, is a very promising approach. Moreover, the potential therapeutic role of A2A AR antagonists to avoid both immunoescaping of tumor cells and tumor development is well documented. Herein, we report on the synthesis and biological evaluation of a new set of piperazine-and piperidine-containing 7-amino-2-(furan-2-yl)thiazolo[5,4-d]pyrimidine derivatives designed as human A2A AR antagonists/inverse agonists. Binding and potency data indicated that a good number of potent and selective hA2A AR inverse agonists were found. Amongst them, the 2-(furan-2-yl)-N5-(2-(4-phenylpiperazin-1-yl)ethyl)thiazolo[5,4-d]pyrimidine-5,7-diamine 11 exhibited the highest A2A AR binding affinity (Ki = 8.62 nM) as well as inverse agonist potency (IC50 = 7.42 nM). In addition, bioinformatics prediction using the web tool SwissADME revealed that 8, 11, and 19 possessed good drug-likeness profiles.
