95704-28-2

Basic information

• Product Name: <(4-Methoxy-phenyl)-diphenyl-methyl>-phosphonsaeure-diaethylester
• Synonyms: <(4-Methoxy-phenyl)-diphenyl-methyl>-phosphonsaeure-diaethylester
• CAS NO: 95704-28-2
• Molecular Weight: 410.45
• Mol File: 95704-28-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: <(4-Methoxy-phenyl)-diphenyl-methyl>-phosphonsaeure-diaethylester(CAS DataBase Reference)
• NIST Chemistry Reference: <(4-Methoxy-phenyl)-diphenyl-methyl>-phosphonsaeure-diaethylester(95704-28-2)
• EPA Substance Registry System: <(4-Methoxy-phenyl)-diphenyl-methyl>-phosphonsaeure-diaethylester(95704-28-2)

Safety Data

• Hazardous Substances Data: 95704-28-2(Hazardous Substances Data)

Upstream product

• 847-83-6 p-methoxytrityl alcohol 
• 762-04-9 phosphonic acid diethyl ester 
• 14992-30-4 4-(α-bromo-benzhydryl)-anisole 
• 2303-76-6 sodium diethyl phosphite 

Relevant articles and documents

A highly efficient nucleophilic substitution reaction between R2P(O)H and triarylmethanols to synthesize phosphorus-substituted triarylmethanes

A highly efficient and general nucleophilic substitution reaction between dialkyl H-phosphonates or diarylphosphine oxides and triarylmethanols catalyzed by HOTf (trifluoromethanesulfonic acid) has been developed. It provides an atom-economical protocol for the synthesis of various symmetrical and unsymmetrical phosphorus-substituted triarylmethanes that constitute an emerging family of potent anticancer agents in rich diversity with 40 to 96% yields. The synthetic applicability of this protocol is demonstrated by gram-scale preparations.