957121-19-6

Basic information

• Product Name: 5-(ethoxycarbonyl)thiophen-3-ylboronic acid
• Synonyms: 5-(ethoxycarbonyl)thiophen-3-ylboronic acid;Ethyl 4-boronothiophene-2-carboxylate, 4-Borono-2-(ethoxycarbonyl)thiophene;5-(ethoxycarbonyl)thiophen-3-yl-3-boronic acid;2-Thiophenecarboxylic acid, 4-borono-, 2-ethyl ester
• CAS NO: 957121-19-6
• Molecular Formula: C7H9BO4S
• Molecular Weight: 200.02
• Product Categories: blocks;BoronicAcids;Carboxes
• Mol File: 957121-19-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-(ethoxycarbonyl)thiophen-3-ylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(ethoxycarbonyl)thiophen-3-ylboronic acid(957121-19-6)
• EPA Substance Registry System: 5-(ethoxycarbonyl)thiophen-3-ylboronic acid(957121-19-6)

Safety Data

• Hazardous Substances Data: 957121-19-6(Hazardous Substances Data)

Usage

Description

5-(Ethoxycarbonyl)thiophen-3-ylboronic acid is an organic compound characterized by the presence of a boronic acid group attached to a thiophene ring. 5-(ethoxycarbonyl)thiophen-3-ylboronic acid features an ethoxycarbonyl group at the 5-position, which contributes to its unique chemical properties and reactivity. It is a versatile reagent in organic synthesis and has potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
5-(Ethoxycarbonyl)thiophen-3-ylboronic acid is used as a synthetic intermediate for the preparation of hydroxyimino(phenyl)propanones, which are GPBAR1 agonists. These agonists have potential therapeutic applications in the treatment of metabolic disorders, such as diabetes and obesity, by modulating glucose and lipid metabolism.
Used in Organic Synthesis:
As a boronic acid derivative, 5-(ethoxycarbonyl)thiophen-3-ylboronic acid can be employed in various cross-coupling reactions, such as Suzuki-Miyaura and Hiyama cross-couplings. These reactions facilitate the formation of carbon-carbon and carbon-heteroatom bonds, enabling the synthesis of complex organic molecules and pharmaceutical compounds.
Used in Material Science:
The unique structure and properties of 5-(ethoxycarbonyl)thiophen-3-ylboronic acid make it a potential candidate for the development of new materials with specific electronic, optical, or magnetic properties. Its incorporation into polymers or other materials could lead to the creation of advanced materials for various applications, such as sensors, electronic devices, or energy storage systems.