957212-74-7Relevant articles and documents
Design and synthesis of potent inhibitors of cholesteryl ester transfer protein (CETP) exploiting a 1,2,3,4-tetrahydroquinoline platform
Rano, Thomas A.,Sieber-McMaster, Ellen,Pelton, Patricia D.,Yang, Maria,Demarest, Keith T.,Kuo, Gee-Hong
scheme or table, p. 2456 - 2460 (2009/12/07)
Tetrahydroquinoline A is a potent inhibitor of the cholesterol ester transfer protein (CETP), a target for the treatment of low HDL-C and atherosclerosis. Low HDL-C has been identified as a key risk factor for cardiovascular disease in addition to high LD