95742-20-4 Usage
General Description
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a chemical compound with the molecular formula C11H14ClN3O. It is a synthetic compound that belongs to the class of 4H-pyrido[1,2-a]pyrimidin-4-one derivatives. 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is an important intermediate in the synthesis of various pharmaceuticals and agrochemicals, and it has potential applications in the development of new therapeutic agents. Its structure contains a chlorine atom, a tetrahydro-2-methyl group, and a pyrido[1,2-a]pyrimidin-4-one ring, which contribute to its unique properties and potential biological activities. 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is of interest to researchers in the fields of medicinal chemistry, organic synthesis, and drug discovery due to its potential pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 95742-20-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,7,4 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 95742-20:
(7*9)+(6*5)+(5*7)+(4*4)+(3*2)+(2*2)+(1*0)=154
154 % 10 = 4
So 95742-20-4 is a valid CAS Registry Number.
95742-20-4Relevant articles and documents
Synthesis and Neuroleptic Activity of 3-(1-Substituted-4-piperidinyl)-1,2-benzisoxazoles
Strupczewski, Joseph T.,Allen, Richard C.,Gardner, Beth Ann,Schmid, Blaine L.,Stache, Ulrich,et al.
, p. 761 - 769 (2007/10/02)
The synthesis of a series of 3-(1-substituted-4-piperidinyl)-1,2-benzisoxazoles is described.The neuroleptic activity of the series was evaluated by utilizing the climbing mice assay and inhibition of spiroperidol binding.Structure-activity relationships were studied by variation of the substituent on the benzisoxazole ring with concomitant variation of four different 1-piperidinyl substituents.Maximum neuroleptic activity was realized when there was a 6-fluoro substituent on the benzisoxazole ring.The 1-piperidinyl substituent appeared less significant, although in most cases, the (1,3-dihydro-2-oxo-2H-benzimidazol-1-yl)propyl group imparted maximum potency.The most potent compound in both assays was 6-fluoro-3--4-piperidinyl>-1,2-benzisoxazole (11b).
