957485-64-2 Usage
Description
FPH2, also known as BRD-9424 or functional proliferation hit 2, is a small molecule that specifically induces the proliferation of primary human hepatocytes in vitro. This unique property makes it a promising candidate for various applications in the field of regenerative medicine and liver research.
Uses
Used in Regenerative Medicine:
FPH2 is used as a hepatocyte proliferation agent for promoting liver regeneration and repair. Its ability to stimulate the growth of primary human hepatocytes makes it a valuable tool for developing novel therapies to treat liver diseases and injuries.
Used in Liver Research:
FPH2 is used as a research tool for studying the mechanisms of liver regeneration and hepatocyte proliferation. By understanding how FPH2 induces hepatocyte growth, researchers can gain insights into the complex processes of liver repair and develop new strategies for treating liver-related disorders.
Used in Drug Development:
FPH2 is used as a screening agent for identifying potential therapeutic compounds that can promote liver regeneration. By testing the effects of various compounds on hepatocyte proliferation in the presence of FPH2, researchers can discover new drugs that may have therapeutic benefits for liver diseases.
Used in Tissue Engineering:
FPH2 is used as a component in bioengineered liver constructs to enhance the growth and functionality of hepatocytes within the engineered tissue. Incorporating FPH2 into tissue engineering strategies can improve the success of liver tissue regeneration and create more effective treatments for liver failure and other liver-related conditions.
Used in Toxicology Studies:
FPH2 is used as a tool in toxicology research to evaluate the effects of various substances on hepatocyte proliferation and liver function. By monitoring the response of hepatocytes to different toxins in the presence of FPH2, researchers can better understand the mechanisms of liver injury and identify potential protective agents.
references
[1]. shan j, schwartz re, ross nt, et al. identification of small molecules for human hepatocyte expansion and ips differentiation. nat chem biol, 2013, 9(8): 514-520.
Check Digit Verification of cas no
The CAS Registry Mumber 957485-64-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,7,4,8 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 957485-64:
(8*9)+(7*5)+(6*7)+(5*4)+(4*8)+(3*5)+(2*6)+(1*4)=232
232 % 10 = 2
So 957485-64-2 is a valid CAS Registry Number.
