958643-19-1

Basic information

• Product Name: 1-benzyl-2-fluoroaziridine
• Synonyms: 1-benzyl-2-fluoroaziridine
• CAS NO: 958643-19-1
• Molecular Weight: 151.184
• Mol File: 958643-19-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-2-fluoroaziridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-2-fluoroaziridine(958643-19-1)
• EPA Substance Registry System: 1-benzyl-2-fluoroaziridine(958643-19-1)

Safety Data

• Hazardous Substances Data: 958643-19-1(Hazardous Substances Data)

Upstream product

• 216578-83-5 (RS)-N-benzyl-2-chloro-2-fluoroethanamide 
• 958643-13-5 N-benzyl-N-(2-chloro-2-fluoroethyl)amine 
• 100-46-9 benzylamine 

Downstream Products

• 958643-13-5 N-benzyl-N-(2-chloro-2-fluoroethyl)amine 

Relevant articles and documents

Synthesis and reactivity of 1-substituted 2-fluoro- and 2,2-difluoroaziridines

(Chemical Equation Presented) A straightforward synthesis toward 2-fluorinated aziridines was developed via ring closure of β-fluorinated β-chloroamines, which were obtained via reduction of the corresponding α-fluorinated amides by borane. When 1-benzyl-2-fluoroaziridine was treated with methanol, reaction occurred at the 2-position, giving rise to N-benzyl-2,2-dimethoxyethylamine, while in the case of 1-benzyl-2,2- difluoroaziridine the 3-position was attacked, giving rise to N-benzyl-2-methoxyacetamide. These reactions point to the divergent reactive behavior of monofluoro- and difluoroaziridines.