959840-95-0

Basic information

• Product Name: C₂₄H₃₀FN₅O₃
• CAS NO: 959840-95-0
• Molecular Weight: 455.532
• Mol File: 959840-95-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₃₀FN₅O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₃₀FN₅O₃(959840-95-0)
• EPA Substance Registry System: C₂₄H₃₀FN₅O₃(959840-95-0)

Safety Data

• Hazardous Substances Data: 959840-95-0(Hazardous Substances Data)

Upstream product

• 959840-11-0 6-[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2H)-one 
• 119111-65-8 1-(N,N-dimethylamino)cyclopropanecarboxylic acid 

Relevant articles and documents

Development of substituted 6-[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2H)-ones as potent poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors active in BRCA deficient cells

We describe an extensive SAR study in the 6-[4-fluoro-3-(substituted)benzyl]-4,5-dimethylpyridazin-3(2H)-one series which led to the identification of potent PARP-1 inhibitors, capable of inhibiting the proliferation of BRCA-1 deficient cancer cells in th