959996-08-8

Basic information

• Product Name: tert-butyl 3-(phenylamino)butanoate
• Synonyms: tert-butyl 3-(phenylamino)butanoate
• CAS NO: 959996-08-8
• Molecular Weight: 235.326
• Mol File: 959996-08-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-(phenylamino)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(phenylamino)butanoate(959996-08-8)
• EPA Substance Registry System: tert-butyl 3-(phenylamino)butanoate(959996-08-8)

Safety Data

• Hazardous Substances Data: 959996-08-8(Hazardous Substances Data)

Upstream product

• 859231-95-1 tert-butyl (Z)-3-(phenylamino)but-2-enoate 
• 97289-74-2 tert-butyl 3-(phenylamino)but-2-enoate 
• 1694-31-1 tert-butyl acetoacetate 
• 62-53-3 aniline 

Downstream Products

• 959996-28-2 tert-butyl 3-(N-phenylpyridine-2-sulfonamido)butanoate 

Relevant articles and documents

Hydrogenation of β-N-substituted enaminoesters in the presence of ruthenium catalysts

β-Aminoesters were prepared in two simple steps from β-ketoesters derivatives and primary amines under mild conditions. Their hydrogenation was performed at 50 °C in the presence of several organometallic catalysts under acidic conditions. The new β-N-substituted aminoesters were isolated in moderate to good yields.

Fused, Tricyclic Sulfonamide Inhibitors of Gamma Secretase

The invention provides compounds of formula I: or pharmaceutically salts thereof where R1, R2, and the A, B, and C-rings are as defined herein. Compounds of formula I are useful in treating or preventing cognitive disorders, such as Alzheimer's disease. The invention also encompasses pharmaceutical compositions comprising compounds or salts of formula I, methods of preparing the desired compounds, and methods of treating cognitive disorders, such as Alzheimer's disease, using the compounds or salts of formula I.