960161-30-2Relevant articles and documents
One pot synthesis of novel α,β-dichloro-β-trifluoromethylated enones and their application to the synthesis of trifluoromethylated heterocycles
Jeon, Sung Lan,Kim, Joa Kyum,Son, Jang Bae,Kim, Bum Tae,Jeong, In Howa
, p. 153 - 157 (2008/03/13)
Trifluoropropynyllithium was reacted with 1 equiv of Weinreb benzamides in THF at -78 to 0 °C, followed by treatment with 4 equiv of trifluoromethanesulfonyl chloride to give α,β-dichloro-β-trifluoromethylated enones 1 in 61-68% yield. The reactions of 1a