960161-55-1

Basic information

• Product Name: N-(4-methylbenzenesulfonyl)imidoylacetic acid (dimethoxycarbonyl)methyl ester
• Synonyms: N-(4-methylbenzenesulfonyl)imidoylacetic acid (dimethoxycarbonyl)methyl ester
• CAS NO: 960161-55-1
• Molecular Weight: 343.357
• Mol File: 960161-55-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(4-methylbenzenesulfonyl)imidoylacetic acid (dimethoxycarbonyl)methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methylbenzenesulfonyl)imidoylacetic acid (dimethoxycarbonyl)methyl ester(960161-55-1)
• EPA Substance Registry System: N-(4-methylbenzenesulfonyl)imidoylacetic acid (dimethoxycarbonyl)methyl ester(960161-55-1)

Safety Data

• Hazardous Substances Data: 960161-55-1(Hazardous Substances Data)

Upstream product

• 6773-29-1 dimethyl diazomalonate 
• 1888-33-1 N-acetyl-(4-methylbenzene)sulfonamide 

Downstream Products

• 34259-29-5 dimethyl 2-hydroxymalonate 

Relevant articles and documents

Chemistry of diazocarbonyl compounds: XXVIII. Reaction of acyclic N-arylsulfonylacetamides with Rh(II)-carbenoids as a new synthetic route to alkyl acetimidoates

A new procedure was proposed for the synthesis of alkyl acetimidoates via alkylation of the carbonyl group in N-arylsulfonylacetamides with Rh(II)-carbenoids. The procedure ensures preparation in good yield of acetimidoates having a polyfunctionalized O-alkyl group. The obtained alkyl acetimidoates in crystal exist as E isomers with respect to the C=N bond and as s-cis conformers relative to the C-OCHRR' bond. Alkyl N- arylsulfonylacetimidoates react with ammonia and hydrazine hydrate to give in good yield the corresponding carboximidamides(hydrazides) via replacement of the O-alkyl group. Unlike structurally related compounds having simple alkyl or aryl groups on the nitrogen atom, N-arylsulfonylacetimidoates readily undergo hydrolysis in the presence of moisture and traces of acids.