960608-47-3

Basic information

• Product Name: 5-chloro-2-(phenylethynyl) aniline
• Synonyms: 5-chloro-2-(phenylethynyl) aniline
• CAS NO: 960608-47-3
• Molecular Weight: 227.693
• Mol File: 960608-47-3.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: 5-chloro-2-(phenylethynyl) aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-(phenylethynyl) aniline(960608-47-3)
• EPA Substance Registry System: 5-chloro-2-(phenylethynyl) aniline(960608-47-3)

Safety Data

• Hazardous Substances Data: 960608-47-3(Hazardous Substances Data)

Upstream product

• 6828-35-9 5-chloro-2-iodoaniline 
• 536-74-3 phenylacetylene 
• 106-47-8 4-chloro-aniline 
• 89-63-4 4-Chloro-2-nitroaniline 
• 5446-05-9 4-chloro-2-nitroiodobenzene 
• 1262543-88-3 2-bromo-4-chloro-1-(phenylethynyl)benzene 

Downstream Products

• 1333392-23-6 2-azido-4-chloro-1-(phenylethynyl)benzene 
• 1637412-29-3 C₁₉H₁₆ClNO 

Relevant articles and documents

Copper-Catalyzed Aerobic Oxidative Cyclization of 2-Alkynylanilines with Nitrosoarenes: Synthesis of Organic Solid Mechanoluminescence Compounds of 4-Oxo-4 H-cinnolin-2-ium-1-ide

An efficient Cu(I)/DMAP/air system for the one-pot synthesis of 4-oxo-4H-cinnolin-2-ium-1-ides, which are often difficult to prepare by traditional routes from substituted 2-alkynylanilines and nitrosoarenes, was developed. These 4-oxo-4H-cinnolin-2-ium-1-ides have practical applications as mechanoluminescent materials. Preliminary mechanistic experiments were performed, and a plausible mechanism for this tandem process is proposed. The use of an inexpensive copper catalyst and molecular oxygen as the oxygen source and the oxidant make this an attractive green protocol with potential synthetic applications.

Gold(I)-Catalyzed Reactions between N-(o-Alkynylphenyl)imines and Vinyldiazo Ketones to Form 3-(Furan-2-ylmethyl)-1 H-indoles via Postulated Azallyl Gold and Allylic Cation Intermediates

This work describes gold-catalyzed additions of vinyldiazo ketones to N-(o-alkynylphenyl)imines to yield 3-(furan-2-ylmethyl)-1H-indoles involving skeletal rearrangement; these new catalytic reactions are applicable to a wide range of substrates. We postu

Nickel-catalyzed cyclization of 1,7-enynes for the selective synthesis of dihydrocyclobuta[c]quinolin-3-ones and benzo[b]azocin-2-ones

We herein described a nickel-catalyzed cyclization ofN-(o-ethynylaryl)acrylamides for the selective synthesis of dihydrocyclobuta[c]quinolin-3-ones and benzo[b]azocin-2-ones. The two varied products could be easily obtained by tuning the reaction temperature. This reaction features easy temperature-control, high efficiency, and gram-scale synthesis.