961-61-5

Basic information

• Product Name: N-methyl-4-nitro-N-phenylbenzamide
• Synonyms: N-methyl-4-nitro-N-phenylbenzamide;4-Nitro-N-methyl-N-phenylbenzamide;N-Methyl-N-phenyl-4-nitrobenzamide;N-Phenyl-N-methyl-4-nitrobenzamide
• CAS NO: 961-61-5
• Molecular Formula: C₁₄H₁₂N₂O₃
• Molecular Weight: 256.26
• Mol File: 961-61-5.mol
• Article Data: 31

Chemical Properties

• Boiling Point: 435.2°C at 760 mmHg
• Flash Point: 217°C
• Appearance: /
• Density: 1.289g/cm³
• Vapor Pressure: 8.93E-08mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: N-methyl-4-nitro-N-phenylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-4-nitro-N-phenylbenzamide(961-61-5)
• EPA Substance Registry System: N-methyl-4-nitro-N-phenylbenzamide(961-61-5)

Safety Data

• Hazardous Substances Data: 961-61-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H12N2O3/c1-15(12-5-3-2-4-6-12)14(17)11-7-9-13(10-8-11)16(18)19/h2-10H,1H3

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 100-61-8 N-methylaniline 
• 3460-11-5 4-nitrobenzanilide 
• 74-88-4 methyl iodide 
• 16118-27-7 4-Nitro-benzoyloxythioameisensaeure-S-, 4-Nitro-benzoesaeure--anhydrid 
• 62-23-7 4-nitro-benzoic acid 
• 61821-45-2 N-methyl-p-nitrothiobenzanilide 
• 636-98-6 p-nitrobenzene iodide 
• 201230-82-2 carbon monoxide 
• 121-69-7 N,N-dimethyl-aniline 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 61821-45-2 N-methyl-p-nitrothiobenzanilide 
• 27689-97-0 trimethyl 4-nitroorthobenzoate 
• 100-61-8 N-methylaniline 
• 14309-78-5 3-Amino-N-methyl-N-phenyl-benzamide 
• 948308-94-9 N-methyl-N-phenyl-4-hydroxylaminobenzamide 
• 784-94-1 p-amino-N-methyl-N-phenylbenzamide 
• 1382354-39-3 C₂₁H₁₈N₂O₃ 
• 1382353-95-8 4-(2-carbamoylphenylamino)-N-methyl-N-phenylbenzamide 
• 1382354-35-9 methyl 2-{4-(methylphenylcarbamoyl)phenylamino}benzoate 
• 784-94-1 C₁₄H₁₄N₂O 
• 1477586-03-0 N-phenyl-N-methyl-ap-(methylamino)benzamide 
• 1646189-19-6 N-phenyl-N-methyl-p-(benzylamino)benzamide 
• 1646189-20-9 N-phenyl-N-methyl-p-(phenylamino)benzamide 
• 5100-28-7 N-phenyl-N-methyl-p-(ethoxycarbonylamino)benzamide 

Relevant articles and documents

N-Heterocyclic Carbene/Cobalt Cooperative Catalysis for the Chemo- and Regioselective C?N Bond Formation between Aldehyde and Amines/Amides

A novel methodology for the construction of various secondary (4 examples), tertiary amides (31 examples), and imides (16 examples) by a Cobalt(II) catalyzed oxidative amide coupling in aqueous media. The Co(III)-TMC was reacted with N-Heteroatom Carbene to form active catalyst Co(II)NHC-TMC in situ which involves in the coordination with Breslow's intermediate and SET for the activation of aldehyde and amides. The mechanism for activation of amide and amine differs on the basis of SET based nucleophilic addition and ligand exchange respectively. The regeneration of the catalyst was achieved using Fe(III)(EDTA)-H2O2 as oxidant. The use of Co(II)TMC-O2 was also found equally efficient in the process. The method is found regioselective for N?H activation in the presence of equally susceptible ortho-C?H bond activation. And amines were found more susceptible then the corresponding amide for the reaction.

Palladium-catalyzed aminocarbonylation of aryl iodides with amides and N-alkyl anilines

A novel and efficient palladium-catalyzed aminocarbonylation of aryl iodides with amides and N-alkyl anilines has been developed. The reaction tolerates a wide range of functional groups and is a reliable method for the rapid synthesis of a variety of valuable imides and tertiary benzanilides under an atmospheric pressure of CO. Copyright

TiCl4 hiocarbonyls and oxidation of sulfides in the presence of H2O2

H2O2 in combination with TiCl4 proved to be a highly reactive reagent system for the desulfurization of thioamide and thioketone derivatives in excellent yields and short reaction times with high purity. Sulfides were also found to undergo oxidation to sulfones under similar reaction conditions. In most cases, these reactions are highly selective, simple, and clean, affording products in high yields and purity.