96122-89-3

Basic information

• Product Name: 1-ethoxycarbonyl-4-(2-tolyl)piperidin-4-ol
• CAS NO: 96122-89-3
• Molecular Weight: 263.337
• Mol File: 96122-89-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-ethoxycarbonyl-4-(2-tolyl)piperidin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethoxycarbonyl-4-(2-tolyl)piperidin-4-ol(96122-89-3)
• EPA Substance Registry System: 1-ethoxycarbonyl-4-(2-tolyl)piperidin-4-ol(96122-89-3)

Safety Data

• Hazardous Substances Data: 96122-89-3(Hazardous Substances Data)

Upstream product

• 95-46-5 2-methylphenyl bromide 
• 29976-53-2 N-ethoxycarbonyl-4-piperidone 
• 932-31-0 ortho-tolylmagnesium bromide 

Downstream Products

• 83674-76-4 4-(2-methylphenyl)-4-hydroxypiperidine 
• 870991-64-3 4-phenylsulfanyl-4-o-tolyl-piperidine-1-carboxylic acid ethyl ester 
• 96122-81-5 1-{2-[(4-Bromo-phenyl)-(4-fluoro-phenyl)-methoxy]-ethyl}-4-o-tolyl-piperidin-4-ol 
• 96141-83-2 1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-o-tolyl-piperidin-4-ol 

Relevant articles and documents

Molecular-modeling based design, synthesis, and activity of substituted piperidines as γ-secretase inhibitors

Alzheimer's disease (AD) is a debilitating disease widely thought to be associated with the accumulation of beta amyloid (Aβ) in the brain. Inhibition of γ-secretase, one of the enzymes responsible for Aβ production, may be a useful strategy for the treatment of AD. Described below is a series of γ-secretase inhibitors designed from a scaffold identified by a ROCS [J. Comput. Chem. 1996, 17, 1653] search of the corporate database.