96139-73-0

Basic information

• Product Name: 2H-Imidazol-2-one, 1,3-dihydro-4-(4-nitrophenyl)-
• CAS NO: 96139-73-0
• Molecular Formula: C9H7N3O3
• Molecular Weight: 205.173
• Mol File: 96139-73-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2H-Imidazol-2-one, 1,3-dihydro-4-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Imidazol-2-one, 1,3-dihydro-4-(4-nitrophenyl)-(96139-73-0)
• EPA Substance Registry System: 2H-Imidazol-2-one, 1,3-dihydro-4-(4-nitrophenyl)-(96139-73-0)

Safety Data

• Hazardous Substances Data: 96139-73-0(Hazardous Substances Data)

Upstream product

• 99-81-0 4-Nitrophenacyl bromide 
• 590-28-3 potassium cyanate 
• 5425-81-0 2-amino-1-(4-nitrophenyl)ethanone hydrochloride 

Relevant articles and documents

Synthesis and anticonvulsant activity of some new 4-aryl-4-imidazoline-2-one derivatives

In this study, some new 4-aryl-4-imidazoline-2-one deriratives have been prepared by the reaction of potassium cyanate with some aminoethanone hydrochlorides. The structure of these compounds have been confirmed by UV, IR, 1H-NMR and elementary analysis. Their anticonvulsant activities were determined by maximal electroshock (MTS) and subcutaneous metrazol (scMet) tests according to the ADD (Antiepileptic Drug Development) programme Phase I. Neurotoxicity of the compounds was evaluated by rotarod test. While 2 of the compounds showed protection against ScMet induced seizures at 30 and 300 mg/kg dose levels, 3 of the compounds showed neurotoxicity.