96141-37-6

Basic information

• Product Name: 3'-O-benzyl-2'-deoxy-5-trifluoromethyluridine
• Synonyms: 3'-O-benzyl-2'-deoxy-5-trifluoromethyluridine
• CAS NO: 96141-37-6
• Molecular Formula: C₁₇H₁₇F₃N₂O₅
• Molecular Weight: 386.324
• Mol File: 96141-37-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.48g/cm³
• Refractive Index: 1.576
• CAS DataBase Reference: 3'-O-benzyl-2'-deoxy-5-trifluoromethyluridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-O-benzyl-2'-deoxy-5-trifluoromethyluridine(96141-37-6)
• EPA Substance Registry System: 3'-O-benzyl-2'-deoxy-5-trifluoromethyluridine(96141-37-6)

Safety Data

• Hazardous Substances Data: 96141-37-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H17F3N2O5/c18-17(19,20)11-7-22(16(25)21-15(11)24)14-6-12(13(8-23)27-14)26-9-10-4-2-1-3-5-10/h1-5,7,12-14,23H,6,8-9H2,(H,21,24,25)/t12-,13+,14+/m0/s1

Upstream product

• 75-63-8 Bromotrifluoromethane 
• 126862-77-9 3'-O-benzyl-2'-deoxy-5-iodouridine 
• 110861-70-6 3'-O-benzyl-2'-deoxy-5-trifluoromethyl-5'-O-trityliuridine 
• 126862-85-9 3'-O-benzyl-2'-deoxy-O⁴-ethyl-5-trifluoromethyl-5'-O-trityluridine 
• 95969-78-1 N³-benzoyl-3'-O-benzyl-2'-deoxy-5-(trifluoromethyl)uridine 
• 100-39-0 benzyl bromide 
• 95969-47-4 N³-benzoyl-2'-deoxy-5-(trifluoromethyl)uridine 
• 951-78-0 2'-deoxyuridine 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 54-42-2 5-Iodo-2'-deoxyuridine 
• 123606-62-2 5'-O-Benzoyl-2'-desoxy-β-D-ribofuranosyluracil 
• 1956-30-5 3',5'-O-diacetyl-5-iodo-2'-deoxyuridine 
• 126862-82-6 2'-deoxy-O⁴-ethyl-5-iodouridine 
• 84043-31-2 5'-O-benzoyl-2'-deoxy-5-iodouridine 

Relevant articles and documents

2-deoxyuridines and riboside precursors

A process is provided for the preparation of certain 2-deoxyuridines including the steps forming a substituted alkyl 5-O-"protected"-2-deoxyribofuranoside, hydrocarbylating the latter compound, and condensing the hydrocarbylated compound in the presence o

Studies on antitumor agents. 8. Antitumor activities of O-alkyl derivatives of 2'-deoxy-5-(trifluoromethyl)uridine and 2'-deoxy-5-fluorouridine

O-Benzyl and O-ethyl derivatives of 2'-deoxy-5-(trifluoromethyl)uridine (F3Thd) and 2'-deoxy-5-fluorouridine (FUdR) were synthesized. The oral antitumor activity of the compounds against sarcoma 180 in mice was examined. The 5'-O-ethyl (3b), 3'