96185-38-5Relevant articles and documents
Ring-opening of NH-aziridines with thiols in ionic liquids: Application to the synthesis of aminosulfide catalysts for asymmetric epoxidation of aldehydes
Namutebi, Mariam,McGarrigle, Eoghan M.,Aggarwal, Varinder K.
experimental part, p. 1250 - 1272 (2010/08/21)
The ring opening of NH-aziridines with thiols was found to proceed in good yield at room temperature in the presence of an ionic liquid1-butyl-3- methylimidazolium chloride (BMIM chloride). This mild methodology was applied to the synthesis of a camphor-derived chiral aminosulfide. The sulfide was used to generate a sulfur ylide, which effected an asymmetric epoxidation of benzaldehyde (e.r. 85:15, trans:cis 90:10, 87% yield). The amino group enabled easy recovery of the sulfide (98% yield) after the reaction by a simple acid/base extraction. Copyright Taylor & Francis Group.
Synthesis and evaluation of N,S-compounds as chiral ligands for transfer hydrogenation of acetophenone
Ekegren, Jenny K.,Roth, Peter,Kaellstroem, Klas,Tarnai, Tibor,Andersson, Pher G.
, p. 358 - 366 (2007/10/03)
New nitrogen- and sulfur-containing compounds, bicyclic and monocyclic, were prepared and evaluated as ligands in the transfer hydrogenation of acetophenone. Utilising [Ir(COD)Cl]2 as metal precursor the best result, 80% ee, was obtained using
