96402-43-6

Basic information

• Product Name: Z-D-1-NAL-OH
• Synonyms: CBZ-(R)-2-AMINO-3-(NAPHTHALEN-1-YL)PROPANOIC ACID;CBZ-3-(1-NAPHTHYL)-D-ALA;CBZ -D-1-NAPHTHYLALANINE;RARECHEM AL CF 0898;N-ALPHA-CARBOBENZOXY-3-(1-NAPHTHYL)-D-ALANINE;Z-D-ALA(1-NAPH)-OH;Z-D-ALA(1-NAPHTHYL)-OH;Z-D-1-NAL-OH
• CAS NO: 96402-43-6
• Molecular Formula: C21H19NO4
• Molecular Weight: 349.38
• Mol File: 96402-43-6.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Z-D-1-NAL-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-D-1-NAL-OH(96402-43-6)
• EPA Substance Registry System: Z-D-1-NAL-OH(96402-43-6)

Safety Data

• Hazardous Substances Data: 96402-43-6(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white powder

Upstream product

• 28095-56-9 2-amino-3-(1-naphthyl)propanoic acid 
• 501-53-1 benzyl chloroformate 
• 55516-54-6 L-1-naphthylalanine 
• 59759-78-3 2-benzoylamino-3-naphthalen-1-yl-propionic acid 

Downstream Products

• 96386-78-6 benzyloxycarbonyl-L-<3-(1-naphthyl)>alanyl-L-histidine hydrazide 
• 89435-66-5 Z-Nal⁽¹⁾-His-Leucinal 
• 96386-80-0 Z-Nal⁽¹⁾-His-Leucinal semicarbazone 

Relevant articles and documents

PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS

Compounds, compositions and methods for preventing, treating or curing a coronavirus, picornavirus, and/or Hepeviridae virus infection in human subjects or other animal hosts. Specific viruses that can be treated include enteroviruses. In one embodiment, the compounds can be used to treat an infection with a severe acute respiratory syndrome virus, such as human coronavirus 229E, SARS, MERS, SARS-CoV-1 (OC43), and SARS-CoV- 2. In another embodiment, the methods are used to treat a patient co-infected with two or more of these viruses, or a combination of one or more of these viruses and norovirus.

Immunomodulators

The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.

TACHYKININ ANTAGONISTS

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