96405-71-9

Basic information

• Product Name: 3-Benzyl-3H-indolo[3,2,1-de][1,5]naphthyridine-5,6-dione
• CAS NO: 96405-71-9
• Molecular Weight: 326.354
• Mol File: 96405-71-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Benzyl-3H-indolo[3,2,1-de][1,5]naphthyridine-5,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Benzyl-3H-indolo[3,2,1-de][1,5]naphthyridine-5,6-dione(96405-71-9)
• EPA Substance Registry System: 3-Benzyl-3H-indolo[3,2,1-de][1,5]naphthyridine-5,6-dione(96405-71-9)

Safety Data

• Hazardous Substances Data: 96405-71-9(Hazardous Substances Data)

Upstream product

• 1016-47-3 N-Acetyltryptamine 
• 61-54-1 tryptamine 
• 486-84-0 harmane 
• 7579-36-4 dibenzyl oxalate 

Downstream Products

• 15071-56-4 5-methoxycanthin-6-one 
• 64118-73-6 5-hydroxy-canthin-6-one 

Relevant articles and documents

Structural development of canthin-5,6-dione moiety as a fluorescent dye and its application to novel fluorescent sensors

Canthin-5,6-dione is a common structure of the fluorescent natural products amarastelline A and nigakinone. Here, we synthesized various derivatives, and studied their fluorescence properties. The effects of substituent groups at the N3-, 4- and 10-positions were clarified. N3-Substitution influenced the solvent-dependent fluorescent change by modulating tautomerization between canthin-5,6-dione and the 5-hydroxy-6-one form. 10-Substitution also influenced the fluorescence, especially in aqueous solution, in combination with N3-substitution. Among the synthesized compounds, 5 showed an ‘OFF-ON-OFF’-type fluorescence change with increase of pH, and therefore served as a novel fluorescent sensor for a specific range of pH. Our findings suggest that canthin-5,6-dione should be useful as a fluorophore moiety for fluorescent labeling of biomolecules and for development of fluorescent probes and sensors.