96499-00-2

Basic information

• Product Name: Benzenamine, 4-chloro-2-(5-phenyl-1,3,4-oxadiazol-2-yl)-
• CAS NO: 96499-00-2
• Molecular Formula: C14H10ClN3O
• Molecular Weight: 271.706
• Mol File: 96499-00-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-chloro-2-(5-phenyl-1,3,4-oxadiazol-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-chloro-2-(5-phenyl-1,3,4-oxadiazol-2-yl)-(96499-00-2)
• EPA Substance Registry System: Benzenamine, 4-chloro-2-(5-phenyl-1,3,4-oxadiazol-2-yl)-(96499-00-2)

Safety Data

• Hazardous Substances Data: 96499-00-2(Hazardous Substances Data)

Upstream product

• 17630-76-1 5-chloroindole 2,3-dione 
• 613-94-5 benzoic acid hydrazide 
• 4743-17-3 5-Chloroisatoic anhydride 
• 5584-15-6 5-chloroanthranilic acid hydrazide 
• 707-07-3 orthobenzoic acid trimethyl ester 

Relevant articles and documents

Electrosynthesis of 2-(1,3,4-Oxadiazol-2-yl)aniline Derivatives with Isatins as Amino-Attached C1 Sources

An intramolecular decarboxylative coupling reaction for the construction of 2-(1,3,4-oxadiazol-2-yl)aniline derivatives was developed from readily available isatins and hydrazides by virtue of electrochemistry. In this reaction, isatins were employed as amino-attached C1 sources, providing a variety of 2-(1,3,4-oxadiazol-2-yl)aniline derivatives with moderate to good yields.

The Chemistry of 2-Aminobenzoyl Hydrazides. 1. Effects of Orthoester Substituents on the Mode of Cyclization

Treatment of substituted 2-aminobenzoyl hydrazides with orthoesters has been found to yield different products depending upon the type of orthoester employed.Equimolar quantities of orthoester and hydrazide yield 3-amino-4(3H)-quinazolinones, whereas utilization of a two-fold excess (or greater) of orthoester yields, in some cases, 3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones as minor products in addition to N-imidate esters as major products.Treatment of hydrazides with trimethyl orthobenzoate yields substituted 5-(2-aminophenyl)-1,3,4-oxadiazoles and 3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones.The steric bulk of the phenyl group in trimethyl orthobenzoate effects the formation of adduct at the β-nitrogen of the hydrazide which cyclized to the oxadiazole and benzotriazepinone products.In the aliphatic orthoester series, the formation of adduct to the aromatic amino group appears to be favored which gives rise to quinazolinone and benzotriazepinone products.