96626-21-0Relevant articles and documents
A Highly Regio- and Stereoselective Syntheses of α-Halo Enamides, Vinyl Thioethers, and Vinyl Ethers with Aqueous Hydrogen Halide in Two-Phase Systems
Cao, Wei,Chen, Ping,Wang, Liang,Wen, Hao,Liu, Yu,Wang, Wanshu,Tang, Yu
, p. 4507 - 4511 (2018/08/09)
A metal-free regio- and stereoselective method is achieved for the preparation of (E)-configured α-halo enamides, vinyl thioethers, and vinyl ethers using aqueous HX (X = F, Cl, Br, I), which features high functional group compatibility and regio- and stereoselectivity, mild conditions, high efficiency, and rapid transformation. Additionally, the isomers could be yielded readily from the (E)-configured α-halo enamides via photocatalysis or under Sonogashira coupling conditions.
The Reduction of Tertiary N-Stryrylsulphonamides and Other Tertiary Sulphonamides by Magnesium and Methanol.
Brettle, Roger,Hilton, Neville A.,Shibib, Sa'ad M.
, p. 3712 - 3720 (2007/10/02)
The preparation of three N-substituted-N-2-phenylethenylsulphonamides is described.On reduction with magnesium and methanol N-phenyl-N-2-phenylethenyltoluene-p-sulphonamide gives cleanly N-phenyl-N-2-phenylethylamine, N-phenyl-N-2-phenylethenylmethanesulphonamide gives some N-phenyl-N-2-phenylethylamine, but also N-phenyl-N-2-phenylethylmethanesulphonamide and N-phenylmethanesulphonamide, and N-cyclohexyl-N-2-phenylethenylmethanesulphonamide gives N-cyclohexyl-N-2-phenylethylmethanesulphonamide and N-cyclohexylmethanesulphonamide.The nitrogen-sulphur bond in N-methyl-N-phenyltoluene-p-sulphonamide and in N-toluene-p-sulphonylpiperidine is also reductively cleaved by magnesium and methanol, but not that in N-methyl-N-phenylmethanesulphonamide.
