96824-28-1 Usage
Description
2-[(4-Acetylphenyl)methyl]cyclopentan-1-one is a chemical compound that serves as a potential metabolite of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID). 2-[(4-Acetylphenyl)methyl]cyclopentan-1-one is characterized by its unique molecular structure, which includes a cyclopentanone ring with a substituted acetylphenylmethyl group. It becomes biologically active after undergoing metabolic processes in the body, where it can exert its effects by inhibiting the activation of cyclooxygenase enzymes.
Uses
Used in Pharmaceutical Industry:
2-[(4-Acetylphenyl)methyl]cyclopentan-1-one is used as an active metabolite for the treatment of inflammation and pain relief. Its role in the metabolism of Loxoprofen contributes to the drug's effectiveness in reducing inflammation and providing analgesic effects. This makes it a valuable component in the development of NSAIDs for various medical applications.
Used in Cardiovascular Applications:
As a metabolite of Loxoprofen, 2-[(4-Acetylphenyl)methyl]cyclopentan-1-one has demonstrated potential in reducing atherosclerosis in mice by lowering inflammation levels. This suggests that it could be utilized in the development of therapeutic agents aimed at treating or preventing cardiovascular diseases associated with inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 96824-28-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,8,2 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 96824-28:
(7*9)+(6*6)+(5*8)+(4*2)+(3*4)+(2*2)+(1*8)=171
171 % 10 = 1
So 96824-28-1 is a valid CAS Registry Number.
96824-28-1Relevant articles and documents
A NEW SYNTHESIS OF SOME NON-STEROIDAL ANTI-INFLAMMATORY AGENTS VIA CYANOPHOSPHATES
Hurusawa, Shinya,Nakamura, Shuji,Yagi, Sayoko,Kurihara, Takushi,Hamada, Yasumasa,Shioiri, Takayuki
, p. 1365 - 1372 (2007/10/02)
A simple and convenient procedure for the syntheses of some non-steroidal anti-inflammatory agents, ibuprofen, rac-naproxen, clidanac and loxoprofen, is described.
