96836-97-4

Basic information

• Product Name: diethyl cyclohexane-trans-1,2-dicarboxylate
• Synonyms: diethyl cyclohexane-trans-1,2-dicarboxylate
• CAS NO: 96836-97-4
• Molecular Weight: 228.288
• Mol File: 96836-97-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: diethyl cyclohexane-trans-1,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl cyclohexane-trans-1,2-dicarboxylate(96836-97-4)
• EPA Substance Registry System: diethyl cyclohexane-trans-1,2-dicarboxylate(96836-97-4)

Safety Data

• Hazardous Substances Data: 96836-97-4(Hazardous Substances Data)

Upstream product

• 13043-60-2 diethyl 1,2,3,6-tetrahydrophthalate 
• 623-91-6 diethyl Fumarate 
• 4841-85-4 trans-1,2-bis(ethoxycarbonyl)-4-cyclohexene 

Downstream Products

• 76155-27-6 (+/-)-trans-2-(hydroxymethyl)cyclohexylmethanol 
• 18886-70-9 (+/-)-trans-cyclohexane-1,2-dicarboxylic acid dihydrazide 
• 116530-96-2 cyclohex-2-ene-1,2-dicarboxylic acid diethyl ester 
• 17351-16-5 trans-1,2-bis(hydroxydiphenylmethyl)cyclohexane 
• 27621-82-5 <2-Diphenylmethylen-cyclohexyl>-diphenyl-methanol 
• 17351-18-7 (+/-)-1,1,3,3-tetraphenyl-trans-octahydro-isobenzofuran 
• 7493-02-9 trans-2-thiahydrindane 
• 3205-36-5 trans-1,2-bis(hydroxymethyl)cyclohexane di-p-toluene-sulfonate 

Relevant articles and documents

Synthesis of 1,4-Cyclohexanedimethanol, 1,4-Cyclohexanedicarboxylic Acid and 1,2-Cyclohexanedicarboxylates from Formaldehyde, Crotonaldehyde and Acrylate/Fumarate

Valuable polyester monomers and plasticizers—1,4-cyclohexanedimethanol (CHDM), 1,4-cyclohexanedicarboxylic acid (CHDA), and 1,2-cyclohexanedicarboxylates—have been prepared by a new strategy. The synthetic processes involve a proline-catalyzed formal [3+1+2] cycloaddition of formaldehyde, crotonaldehyde, and acrylate (or fumarate). CHDM is produced after a subsequent hydrogenation step over a commercially available Cu/Zn/Al catalyst and a one-pot hydrogenation/oxidation/hydrolysis process yields CHDA, whereas 1,2-cyclohexanedicarboxylate is obtained by a Pd/C-catalyzed tandem decarbonylation/hydrogenation step.

NEW COMPOUNDS FOR THE TREATMENT OF CNS DISORDER

The invention relates to novel pyrazolopyrimidinones according to formula (I). The new compounds shall be used for the manufacture of medicaments, in particular medicaments for the treatment of conditions concerning deficits in perception, concentration, learning or memory. The new compounds are also for the manufacture of medicaments for the treatment of Alzheimer's disease. Further aspects of the present invention refer to a process for the manufacture of the compounds and their use for producing medicaments.