96894-91-6

Basic information

• Product Name: Przewaquinone E
• CAS NO: 96894-91-6
• Molecular Weight: 312.322
• Mol File: 96894-91-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Przewaquinone E(CAS DataBase Reference)
• NIST Chemistry Reference: Przewaquinone E(96894-91-6)
• EPA Substance Registry System: Przewaquinone E(96894-91-6)

Safety Data

• Hazardous Substances Data: 96894-91-6(Hazardous Substances Data)

Upstream product

• 77769-21-2 1,6-dimethyl-8,9-dihydrophenanthro[1,2-b]furan-10,11-dione 
• 96839-29-1 6-hydroxy-1,6-dimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione 
• 113297-21-5 4,5-dihydro-3-methylbenzo[1,2-b]furan-4,5-dione 
• 7182-21-0 5-hydroxy-3-methylbenzo<1.2-b>furan 
• 124292-44-0 1-methyl-2-vinylcyclohex-2-en-1-ol 
• 140709-89-3 2-vinylcyclohex-2-en-1-one 
• 33948-36-6 2-iodocyclohex-2-en-1-one 
• 930-68-7 cyclohexenone 
• 127758-21-8 (-)-(5R,6S)-5,6-dihydroxy-6-methyl-1-vinylcyclohexene 5,6-acetonide 

Relevant articles and documents

Total synthesis of (±)-tanshinol B, tanshinone I, and (±)-tanshindiol B and C

A concise and efficient approach was established for the divergent total synthesis of (±)-tanshindiol B and C and tanshinone I from a ubiquitous ene intermediate in 1-2 steps. This critical intermediate was derived from (±)-tanshinol B, which was synthesized in 50% overall yield over 3 steps using an ultrasound-promoted cycloaddition as a key step. Compared to a previously reported strategy, our approach is more step-economic, thus greatly improving the synthetic efficiency. The bioactivity evaluation indicates that the diol stereochemistry of the tanshidiols has an impact on the EZH2 inhibitory activity.