96930-16-4

Basic information

• Product Name: (4R,5S)-4-methyl-5-phenyl-3-phenylacetyl-oxazolidin-2-one
• Synonyms: (4R,5S)-4-methyl-5-phenyl-3-phenylacetyl-oxazolidin-2-one
• CAS NO: 96930-16-4
• Molecular Weight: 295.338
• Mol File: 96930-16-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4R,5S)-4-methyl-5-phenyl-3-phenylacetyl-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-4-methyl-5-phenyl-3-phenylacetyl-oxazolidin-2-one(96930-16-4)
• EPA Substance Registry System: (4R,5S)-4-methyl-5-phenyl-3-phenylacetyl-oxazolidin-2-one(96930-16-4)

Safety Data

• Hazardous Substances Data: 96930-16-4(Hazardous Substances Data)

Upstream product

• 77943-39-6 4-methyl-5-phenyloxazolidin-2-one 
• 103-80-0 phenylacetyl chloride 
• 103-82-2 phenylacetic acid 

Downstream Products

• 77943-39-6 4-methyl-5-phenyloxazolidin-2-one 
• 212790-70-0 (4R,5S)-3-((R)-2-Fluoro-2-phenyl-acetyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 20698-91-3 (R)-methyl mandelate 
• 212790-73-3 (R)-2-fluoro-N-methoxy-N-methyl-2-phenylacetamide 
• 212790-78-8 (R)-2-fluoro-1,2-diphenylethan-1-one 
• 122-78-1 phenylacetaldehyde 
• 96930-31-3 (4R,5S)-3-((R)-2-Hydroxy-2-phenyl-acetyl)-4-methyl-5-phenyl-oxazolidin-2-one 

Relevant articles and documents

SULFONAMIDE DERIVATIVES AS GLYCOKINASE ACTIVATORS USEFUL IN THE TREATMENT OF TYPE 2 DIABETES

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Asymmetric synthesis of optically active 2,3-diarylsuccinic acids by oxidative homocoupling of chiral 3-(arylacetyl)-2-oxazolidones

Oxidative homocoupling of chiral 3-(arylacetyl)-2-oxazolidones 1 was achieved by treatment with DABCO-TiCl4 or DMAP-TiCl4 and afforded the corresponding dimers stereospecifically. The reaction of (4S)- and (4R)-substituted 1 gave (S,S)- and (R,R)-dimers respectively. The obtained dimers were easily transformed to the corresponding 2,3-diaryl succinic acids. This reaction therefore provides a useful method For the synthesis of optically pure 2,3-diarylsuccinic acids. The oxidative coupling was not inhibited by para substitution of an electron donating group on the aryl group. A para-substituted electron withdrawing group and an ortho-substituent, however, hindered the coupling.