96994-72-8

Basic information

• Product Name: 3-chloro-4-(N,N-dimethylamino)benzonitrile
• Synonyms: 3-chloro-4-(N,N-dimethylamino)benzonitrile
• CAS NO: 96994-72-8
• Molecular Weight: 180.637
• Mol File: 96994-72-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-chloro-4-(N,N-dimethylamino)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-4-(N,N-dimethylamino)benzonitrile(96994-72-8)
• EPA Substance Registry System: 3-chloro-4-(N,N-dimethylamino)benzonitrile(96994-72-8)

Safety Data

• Hazardous Substances Data: 96994-72-8(Hazardous Substances Data)

Upstream product

• 1197-19-9 4-cyano-N,N-dimethylaniline 
• 680-31-9 N,N,N,N,N,N-hexamethylphosphoric triamide 
• 6574-99-8 3,4-dichloro-benzonitrile 
• 1428637-03-9 C₁₀H₁₃ClN₂O 
• 137042-67-2 3-bromo-4-methoxybenzonitrile 

Downstream Products

• 1026565-13-8 2-(3-Chloro-4-dimethylamino-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-4,5-dihydro-1H-imidazol-4-ol 
• 1428637-21-1 2-chloro-N,N-dimethyl-4-(1H-tetrazol-5-yl)aniline 

Relevant articles and documents

Synthesis of Halogenated Anilines by Treatment of N, N-Dialkylaniline N-Oxides with Thionyl Halides

The special reactivity of N,N-dialkylaniline N-oxides allows practical and convenient access to electron-rich aryl halides. A complementary pair of reaction protocols allow for the selective para-bromination or ortho-chlorination of N,N-dialkylanilines in up to 69% isolated yield. The generation of a diverse array of halogenated anilines is made possible by a temporary oxidation level increase of N,N-dialkylanilines to the corresponding N,N-dialkylaniline N-oxides and the excision of the resultant weak N-O bond via treatment with thionyl bromide or thionyl chloride at low temperature.

2-ARYL- AND 2-HETEROARYLTHIAZOLYL COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF

The present invention discloses fused bicyclic 2-aryl- or 2-heteroarylthiazolyl compounds and their pharmaceutically acceptable salts and esters thereof, which are useful for inhibiting the growth of cancerous cells, inhibiting human breast carcinoma tumo