97004-08-5Relevant articles and documents
Synthesis of praziquantel via N-acyliminium ion cyclization of amtoo acetals through several synthetic routes
Kim, Joong Hyup,Lee, Yong Sup,Kim, Choong Sup
, p. 2279 - 2285 (2007/10/03)
Syntheses of praziquantel have been accomplished via an N-acyliminium ion by several routes including the tandem nucleophilic addition-cyclization sequence from amido acetal (8) or (10) and a stepwise cyclization of enamide (9) generated from the nucleophilic addition reaction of amido acetal (8) or (10).