97023-74-0

Basic information

• Product Name: 1,5-Hexanedione, 1-(4-methylphenyl)-
• CAS NO: 97023-74-0
• Molecular Formula: C13H16O2
• Molecular Weight: 204.269
• Mol File: 97023-74-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,5-Hexanedione, 1-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Hexanedione, 1-(4-methylphenyl)-(97023-74-0)
• EPA Substance Registry System: 1,5-Hexanedione, 1-(4-methylphenyl)-(97023-74-0)

Safety Data

• Hazardous Substances Data: 97023-74-0(Hazardous Substances Data)

Upstream product

• 1119-51-3 bromopentene 
• 138174-24-0 1-(p-tolyl)hex-5-en-1-one 
• 71434-57-6 1-(p-tolyl)hex-5-en-1-ol 
• 104-87-0 4-methyl-benzaldehyde 
• 116931-71-6 1,5-bis(1-methyl-1H-imidazol-2-yl)-5-(trimethylsilyloxy)hexan-1-one 
• 116931-62-5 1,5-bis(1-methyl-1H-imidazol-2-yl)-5-hydroxyhexan-1-one 
• 116931-57-8 1,5-bis(1-methyl-1H-imidazol-2-yl)pentane-1,5-dione 
• 116931-54-5 1,1'-glutaryldipyrrolidine 
• 1119-40-0 Dimethyl glutarate 
• 106-38-7 para-bromotoluene 
• 1120-72-5 2-Methylcyclopentanone 
• 3128-06-1 5-ketohexanoic acid 
• 108-88-3 toluene 
• 97704-16-0 2-Methyl-1-p-tolyl-cyclopentanol 

Relevant articles and documents

Cyclopentane Formation from Flexible Precursors Using Samarium(II) Reagents

Three efficient methods for five-membered ring carbocycle synthesis have been developed from simple starting materials using samarium(II) reagents. A Reformatsky aldol reaction proceeded efficiently with samarium(II) iodide using lithium bromide as an additive. A new intramolecular alkylation of a samarium enolate was realized with a pendant sulfonate ester leaving group. Pinacol cyclization of a simple diketone was also demonstrated giving a diol product in high stereoselectivity. A promising lead result has been established demonstrating enantioselectivity in a chiral ligand controlled Reformatsky aldol reaction.

Chemospecificity in arylations of δ- and γ-ketocarboxylic acids with P2O5-MsOH, TfOH, and related acidic media

Remarkable contrast between chemospecificities in acid-mediated arylation of δ- and γ-ketocarboxylic acids was revealed: in the presence of P2O5-MsOH, TfOH, PPA, and MsOH, arylation of δ-ketocarboxylic acid 1A with arenes takes place

Synthesis and Application of Imidazole Derivatives: Preparation of Various Diketones from 1,n-Bis(1-methyl-1H-imidazol-2-yl)alkane-1,n-diones

Reaction of 1,n-bis(1-methyl-1H-imidazol-2-yl)alkane-1,n-dione (8) with an excess of Grignard reagent was examined.In the cases of n = 4 and 5, precursors (14) for synthesis of various asymmtric 1,4- and 1,5-diketones (12: R1 R2), respectively, were obtained in good yields by treating 8 with an excess of methylmagnesium iodide in ether followed by trimethylsilylation.In the case of n >/= 8, the two carbonyl groups of 8 were both attacked by the Grignard reagent, and the products (11: R1=R2=CH3) were convertible to symmetrical diketones (12: R1=R2=CH3) in good yields.In cases of n = 6 and 7, the mode of the Grignard reaction was transitional between the two types.Keywords - 2-acyl-1H-imidazole; 1,n-bis(1-methyl-1H-imidazol-2-yl)-1,n-alkanedione; diketone synthesis; asymmetric diketone; symmetric diketone; Grignard reaction; dihydrojasmone; cis-jasmone; muscone; 2-(1-hydroxy-1-alkyl)-1-methyl-1H-imidazole