97043-02-2Relevant articles and documents
Synthesis an Biological Effects of Novel Thiocolchicines. 3. Evaluation of N-Acyldeacetylthiocolchicines, N-(Alkoxycarbonyl)deacetylthiocolchicines, and O-Ethyldemethylthiocolchicines. New Synthesis of Thiodemecolcine and Antileukemic Effects of 2-Demethy
Kerekes, Peter,Sharma, Padam N.,Brossi, Arnold,Chignell, Colin F.,Quinn, Frank R.
, p. 1204 - 1208 (2007/10/02)
Novel and known analogues of thiocolchicine were evaluated in a tubulin binding assay in vivo in mice for acute toxicity and in the P338 lymphocytic leukemia assay.This evaluation included N-acyldeacetylthiocolchicines, N-(alkoxycarbonyl)deacetylthiocolch