97091-03-7

Basic information

• Product Name: 5-benzoylamino-2-(p-aminosulfonyl)anilino-4-hydroxy-pyrimidine
• Synonyms: 5-benzoylamino-2-(p-aminosulfonyl)anilino-4-hydroxy-pyrimidine
• CAS NO: 97091-03-7
• Molecular Weight: 385.403
• Mol File: 97091-03-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-benzoylamino-2-(p-aminosulfonyl)anilino-4-hydroxy-pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-benzoylamino-2-(p-aminosulfonyl)anilino-4-hydroxy-pyrimidine(97091-03-7)
• EPA Substance Registry System: 5-benzoylamino-2-(p-aminosulfonyl)anilino-4-hydroxy-pyrimidine(97091-03-7)

Safety Data

• Hazardous Substances Data: 97091-03-7(Hazardous Substances Data)

Upstream product

• 63-74-1 sulfanilamide 
• 97091-02-6 5-benzoylamino-4-hydroxy-2-methylmercapto-pyrimidine 
• 15646-46-5 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one 

Downstream Products

• 77997-19-4 D(-)-α-<3<2-(p-aminosulfonylanilino)-4-hydroxy-5-pyrimidinyl>ureido>-2-(4-hydroxyphenyl)-acetic acid 
• 89074-09-9 2-(p-aminosulfonyl)anilino-5-chlorocarbonylamino-4-hydroxy-pyrimidine 
• 77997-18-3 1-hydro-5-(p-aminosulfonyl)anilino-2-hydroxy-oxazolo<5,4-d>pyrimidine 
• 77997-17-2 5-amino-2-(p-aminosulfonyl)anilino-4-hydroxy-pyrimidine 

Relevant articles and documents

Synthesis and antibacterial activity of pyrimidinylureidopenicillins

The 6R-[(R)-2-[3-[5-pyrimidinyl]ureido]-2-(4-hydroxyphenyl)acetamido]-penicill anic acids, prepared by two synthetic routes, exhibit broad antimicrobial activity against Gram-positive and Gram-negative bacteria. Their structure-activity relationships are discussed. 6R-[(R)-2-[3-[2-(p-aminosulfonyl)anilino-4-hydroxy-5-pyrimidinyl]ureido]-2 -(4-hydroxyphenyl)acetamido]-penicillanic acid, sodium salt (VX-VC 43), the most active compound, shows very low MIC (minimal inhibitory concentration) values against clinically important Gram-negative bacteria, primarily Pseudomonas aeruginosa.