97166-94-4Relevant articles and documents
AuPd?Fe3O4 Nanoparticle Catalysts for Highly Selective, One-Pot Cascade Nitro-Reduction and Reductive Amination
Cho, Ahra,Byun, Sangmoon,Kim, B. Moon
supporting information, p. 1253 - 1261 (2018/02/21)
Exceedingly chemoselective preparation of secondary amines from the cascade reaction of nitro reduction followed by reductive amination of the resulting amine with an aldehyde through the use of bimetallic AuPd alloy nanoparticle catalyst is described. We prepared a AuPd alloy nanocatalyst supported on Fe3O4 in gram scale without calcination. One pot synthesis of a number of secondary amines was achieved from a variety of nitroarenes and aryl or alkyl aldehydes under 1 atm of H2 at room temperature. No N-debenzylation was observed in the case of the reactions involving aryl aldehydes, which is often observed in the reductive amination catalysed by a transition metal catalyst such as palladium. We also accomplished efficient one-pot synthesis of a number of N-aryl substituted isoindolinone derivatives from 1-formylbenzoic acid and several nitroarenes using the same reaction conditions. Furthermore, thanks to the magnetic property of the Fe3O4 support, the AuPd?Fe3O4 NPs could be easily separated and reused up to 20 times without the loss of its catalytic activity. (Figure presented.).
Synthesis of palladacycles employing iminoisoindolines as monoanionic bidentate ligands
Chitanda, Jackson M.,Prokopchuk, Demyan E.,Quail, J. Wilson,Foley, Stephen R.
experimental part, p. 6023 - 6029 (2009/02/08)
A series of air- and moisture-stable iminoisoindoline-based palladacycles have been prepared in two operationally simple steps from commercially available reagents. para-Substituted N,N′-diphenyliminoisoindoline ligands are easily synthesized from phthalaldehyde and para-substituted anilines and further reaction of the iminoisoindoline ligands with Pd(OAc)2 in dichloromethane at room temperature results in formation of six-membered [C,N] dinuclear cyclopalladated complexes with the general formula [(iminoisoindoline)Pd(μ-OAc)]2. The resulting palladacyclic complexes were tested as precatalysts in Heck and Suzuki coupling reactions.
Synthesis of 1,2-Disubstituted Isoindoles from o-Phthalaldehyde and Primary Amines
Nan'ya, Seiko,Tange, Toshiaki,Maekawa, Eturo
, p. 449 - 451 (2007/10/02)
2-Alkyl-1(2-formylphenyl-N-alkyliminomethyl)isoindoles were prepared by the reaction of o-phtalaldehyde with primary amines in 99percent ethanol at 0 deg C. 2-Alkyl-3-alkyliminoisoindolinones were isolated from the reaction mixture as by-products.Their formation mechanism is proposed.
