97187-20-7

Basic information

• Product Name: 5'-<<3-(benzyloxy)propyl>amino>-5'-deoxy-2',3'-O-(1-methylethylidene)adenosine
• Synonyms: 5'-<<3-(benzyloxy)propyl>amino>-5'-deoxy-2',3'-O-(1-methylethylidene)adenosine
• CAS NO: 97187-20-7
• Molecular Weight: 454.529
• Mol File: 97187-20-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-<<3-(benzyloxy)propyl>amino>-5'-deoxy-2',3'-O-(1-methylethylidene)adenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-<<3-(benzyloxy)propyl>amino>-5'-deoxy-2',3'-O-(1-methylethylidene)adenosine(97187-20-7)
• EPA Substance Registry System: 5'-<<3-(benzyloxy)propyl>amino>-5'-deoxy-2',3'-O-(1-methylethylidene)adenosine(97187-20-7)

Safety Data

• Hazardous Substances Data: 97187-20-7(Hazardous Substances Data)

Upstream product

• 5375-00-8 3-benzyloxypropyl iodide 
• 21950-36-7 5'-amino-5'-deoxy-2',3'-O-isopropylideneadenosine 

Relevant articles and documents

Synthesis of 5'--5'-deoxyadenosine

The synthesis of the title compound 2 is described.N-Alkylation of 5'-amino-5'-deoxy-2',3'-O-(1-methylethylidene)adenosine (3) with benzene gave after debenzylation the 5'-deoxyadenosine derivative 4b.After derivatization of the 5'-NH, the terminal hydroxy group was reacted with triphenylphosphane, diethyl azodicarboxylate, and N-hydroxyphthalimide to yield a full protected derivative of 2.Sequential deprotection (H2NNH2, then H2SO4) afforded the target molecule 2 as its sesquisulfate salt.