97188-57-3Relevant articles and documents
Preparation and evaluation of sulfur-containing metal chelators
Clavier, Sylvain,Rist, ystein,Hansen, Stina,Gerlach, Lars-Ole,Hoegberg, Thomas,Bergman, Jan
, p. 4248 - 4253 (2007/10/03)
With a view to probe the structure and function of G-protein coupled receptors the synthesis of functionalized 8-mercaptoquinoline derivatives and 2-(2-pyridyl)thiophenol was achieved. A fluorescence-based method for determining the affinity of these metal chelators toward zinc ions was developed.
The preparation of some fused isothiazole derivatives
McKinnon, David M.,Duncan, K.Ann,McKinnon, Aileen M.,Spevack, Perry A.
, p. 882 - 886 (2007/10/02)
The treatment of di(2-amino-5-methylphenyl)methane with N-sulfinylmethanesulfonamide gives two materials, 3-(2-amino-5-methylphenyl)-5-methyl-2,1-benzisothiazole and what appears to be its tautomer, a 2,1-benzisothiazolo-2,1-benzisothiazole derivative.Reaction of the former with methyl iodide gives mono-, di-, and trimethyl derivatives.The second of these also possesses the symmetrical 2,1-benzisothiazolo-2,1-benzisothiazole structure.The structure of the other methylation product and of the acetylation products are discussed.Some 1,2-dithiol-3-ylidene-2-pyridylmethanes were made by condensation of 3-alkylthio-1,2-dithiolium salts with methyl 2-pyridylacetate.These demonstrate little sulfur-nitrogen interaction. 3-Methylthio-4-phenyl-1,2-dithiolium iodide reacts anomalously with methyl 2-pyridylacetate to form a quinolizinethione. 1,2-Benzisothiazolopyridinium triiodide was made by iodine oxidation of 2-(2-mercaptophenylpyridine).
