97347-28-9

Basic information

• Product Name: NA, NE-BIS-BOC-L-LYSINE TERT-BUTYL ESTER
• Synonyms: NA, NE-BIS-BOC-L-LYSINE TERT-BUTYL ESTER;Na,Ne-Diboc-L-lysinetert-ButylEster;Nα,Nε-Bis-boc-L-lysine tert-Butyl Ester;N2,N6-Bis[(1,1-diMethylethoxy)carbonyl]-L-lysine 1,1-DiMethylethyl Ester;Nα,Nε-Diboc-L-lysine tert-Butyl Ester
• CAS NO: 97347-28-9
• Molecular Formula: C20H38N2O6
• Molecular Weight: 402.528
• Product Categories: Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives
• Mol File: 97347-28-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 94-96°C
• Boiling Point: 507.2°C at 760 mmHg
• Flash Point: 260.5°C
• Appearance: /
• Density: 1.039g/cm³
• Vapor Pressure: 2.08E-10mmHg at 25°C
• Refractive Index: 1.465
• Solubility: Chloroform, Methanol
• CAS DataBase Reference: NA, NE-BIS-BOC-L-LYSINE TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: NA, NE-BIS-BOC-L-LYSINE TERT-BUTYL ESTER(97347-28-9)
• EPA Substance Registry System: NA, NE-BIS-BOC-L-LYSINE TERT-BUTYL ESTER(97347-28-9)

Safety Data

• Hazardous Substances Data: 97347-28-9(Hazardous Substances Data)

Usage

Description

NA, NE-BIS-BOC-L-LYSINE TERT-BUTYL ESTER, with the chemical name Nα,Nε-Bis-boc-L-lysine tert-Butyl Ester (CAS# 97347-28-9), is a white solid compound that plays a significant role in organic synthesis. Its unique structure and properties make it a valuable component in various chemical reactions and processes.

Uses

Used in Organic Synthesis:
NA, NE-BIS-BOC-L-LYSINE TERT-BUTYL ESTER is used as a key intermediate in organic synthesis for the development of complex organic molecules and pharmaceutical compounds. Its ability to participate in various chemical reactions, such as condensation, substitution, and rearrangement, makes it a versatile building block in the synthesis of target molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, NA, NE-BIS-BOC-L-LYSINE TERT-BUTYL ESTER is used as a precursor in the synthesis of peptide-based drugs and other bioactive molecules. Its presence in the synthesis process allows for the creation of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Research and Development:
NA, NE-BIS-BOC-L-LYSINE TERT-BUTYL ESTER is also utilized in research and development settings to explore new chemical reactions, mechanisms, and pathways. Its unique properties and reactivity make it an essential tool for chemists and researchers working on the discovery and optimization of new chemical entities.
Overall, NA, NE-BIS-BOC-L-LYSINE TERT-BUTYL ESTER is a crucial compound in the fields of organic synthesis, pharmaceutical development, and research, contributing to the advancement of science and medicine through its diverse applications.

InChI:InChI=1/C20H38N2O6/c1-18(2,3)26-15(23)14(22-17(25)28-20(7,8)9)12-10-11-13-21-16(24)27-19(4,5)6/h14H,10-13H2,1-9H3,(H,21,24)(H,22,25)/t14-/m0/s1

Upstream product

• 657-27-2 L-Lysine hydrochloride 
• 75-65-0 tert-butyl alcohol 
• 56-87-1 L-lysine 
• 98946-18-0 tert-Butyl 2,2,2-trichloroacetimidate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 97347-40-5 N^α,N^ca-diBoc-L-2-aminoadipamic acid tert-butyl ester 
• 114659-53-9 N-Boc-6-tert-butoxycarbonylaminopiperidine-2-carboxylic acid tert-butyl ester 
• 167090-40-6 (S)-2-amino-6-hydroxy-hexanoic acid methyl ester 
• 142589-42-2 (S)-N-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxo-3-phenylpropyl]-6-hydroxy-(S)-norleucine methyl ester 
• 7433-32-1 L-2-aminoadipamic acid 
• 1118-90-7 L-homoglutamic acid 

Relevant articles and documents

A novel three-step hydroxy-deamination sequence: Conversion of lysine to 6-hydroxynorleucine derivatives

Oxidation of carbamates with catalytic RuO4, generated from RuO2 and NaBrO3, provides the corresponding acyl carbamates, which can be reduced with NaBH4 to provide alcohols. Application of this methodology to L-lysine provides (S)-6-hydroxynorleucine derivatives.