97389-23-6

Basic information

• Product Name: Benzenamine, 4-[(tetrahydro-2H-pyran-2-yl)oxy]-
• CAS NO: 97389-23-6
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.246
• Mol File: 97389-23-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-[(tetrahydro-2H-pyran-2-yl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-[(tetrahydro-2H-pyran-2-yl)oxy]-(97389-23-6)
• EPA Substance Registry System: Benzenamine, 4-[(tetrahydro-2H-pyran-2-yl)oxy]-(97389-23-6)

Safety Data

• Hazardous Substances Data: 97389-23-6(Hazardous Substances Data)

Upstream product

• 100-02-7 4-nitro-phenol 
• 110-87-2 3,4-dihydro-2H-pyran 
• 123-30-8 4-amino-phenol 
• 694-54-2 tetrahydro-2H-2-pyranol 
• 20443-91-8 2-(4-nitrophenoxy)tetrahydropyran 

Downstream Products

• 174359-47-8 p-tetrahydropyran-2-yloxy-N-(benzyloxycarbonyl)aminobenzene 
• 7107-59-7 4-(N-Benzyloxycarbonylamino)phenol 
• 1026304-66-4 [2-(2-tert-Butoxycarbonylamino-acetylamino)-acetylamino]-acetic acid 4-amino-phenyl ester 
• 174359-50-3 (S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid 4-benzyloxycarbonylamino-phenyl ester 
• 174359-51-4 (2-tert-Butoxycarbonylamino-acetylamino)-acetic acid 4-benzyloxycarbonylamino-phenyl ester 
• 174359-52-5 [2-(2-tert-Butoxycarbonylamino-acetylamino)-acetylamino]-acetic acid 4-benzyloxycarbonylamino-phenyl ester 
• 174359-58-1 N^α-(tert-butyloxycarbonyl)glycylglycine p-(N',N''-bis(benzyloxycarbonyl)guanidino)phenyl ester 
• 174359-59-2 C₃₄H₃₈N₆O₁₀ 
• 174359-61-6 C₃₃H₃₇N₅O₉ 
• 174359-60-5 C₃₃H₃₇N₅O₉ 
• 1025987-97-6 ((R)-2-tert-Butoxycarbonylamino-propionylamino)-acetic acid 4-amino-phenyl ester 
• 1026605-29-7 ((S)-2-tert-Butoxycarbonylamino-propionylamino)-acetic acid 4-amino-phenyl ester 
• 174359-49-0 (R)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester 
• 174359-48-9 (S)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester 

Relevant articles and documents

AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS

In one aspect, the present disclosure provides methods of preparing a primary or secondary amine and hydroxylated aromatic compounds. In some embodiments, the aromatic compound may be unsubstituted, substituted, or contain one or more heteroatoms within the rings of the aromatic compound. The methods described herein may be carried out without the need for transition metal catalysts or harsh reaction conditions.

Selective tetrahydropyranylation under non-acidic conditions

We report that the tetrahydropyranylation of hydroxyl groups, exhibiting especially very low nucleophilicities, can be achieved by means of Mitsunobu reaction with 2-hydroxytetrahydropyran. This reaction led to the protection of phenols and pyridinols without the use of an acidic catalyst. For instance hydroxypyridines could not be protected by dihydropyran under acidic conditions, whereas they underwent a smooth tetrahydropyranylation under Mitsunobu conditions. The method is selective for a phenol over an alcohol. Georg Thieme Verlag Stuttgart.

Synthesis and properties of N(α)-(tert-butyloxycarbonyl)peptide p- guanidinophenyl esters as trypsin substrates

N(α)-(tert-Butyloxycarbonyl)peptide p-guanidinophenyl esters were synthesized by amidination of N(α)-(tert-butyloxycarbonyl)peptide p- aminophenyl esters with 1-[N,N'-bis(benzyloxycarbonyl)amidino]pyrazole, followed by deprotection by catalytic hydrogenation, in good total yields. These synthetic esters were characterized as specific substrates for trypsin, and kinetic parameters for the trypsin-catalyzed hydrolysis are presented.