97398-89-5

Basic information

• Product Name: N-(4-Fluoro-5-methyl-2-nitro-phenyl)-acetamide
• Synonyms: N-(4-Fluoro-5-methyl-2-nitro-phenyl)-acetamide
• CAS NO: 97398-89-5
• Molecular Formula: C₉H₉FN₂O₃
• Molecular Weight: 212.1777632
• Mol File: 97398-89-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-Fluoro-5-methyl-2-nitro-phenyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-Fluoro-5-methyl-2-nitro-phenyl)-acetamide(97398-89-5)
• EPA Substance Registry System: N-(4-Fluoro-5-methyl-2-nitro-phenyl)-acetamide(97398-89-5)

Safety Data

• Hazardous Substances Data: 97398-89-5(Hazardous Substances Data)

Upstream product

• 331-30-6 N-acetyl-4-fluoro-3-methylbenzenamine 
• 455-88-9 5-nitro-2-fluorotoluene 
• 452-69-7 3-methyl-4-fluoroaniline 

Downstream Products

• 95896-78-9 2-amino-3,4,8-trimethylimidazo-[4,5-f]quinoxaline 
• 97389-17-8 3,4,7-trimethyl-3H-imidazo<4,5-f>quinoxalin-2-amine 
• 97389-11-2 4-fluoro-5-methyl-1,2-benzenediamine 

Relevant articles and documents

HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE

The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.

A convenient synthesis of the potent mutagen 3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine.

The highly mutagenic title compound (4,8-DiMeIQx) was synthesized in 13% overall yield from 2-fluoro-5-nitrotoluene in eight operations. The average operation yield was 83%. The reaction sequence used gave, in addition to the title compound, the isomer 3,4,7-trimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine (4,7-DiMeIQx).