97429-95-3

Basic information

• Product Name: 4-(2-chlorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride
• Synonyms: 4-(2-chlorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride
• CAS NO: 97429-95-3
• Molecular Weight: 230.137
• Mol File: 97429-95-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(2-chlorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-chlorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride(97429-95-3)
• EPA Substance Registry System: 4-(2-chlorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride(97429-95-3)

Safety Data

• Hazardous Substances Data: 97429-95-3(Hazardous Substances Data)

Upstream product

• 375853-82-0 tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate 
• 864830-05-7 tert-butyl 4-(2-chlorophenyl)-5,6-dihydropyridine-1(2H)-carboxylate 
• 615-41-8 2-iodochlorobenzene 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 694-80-4 2-bromo-1-chlorobenzene 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 553630-94-7 4-(2-chlorophenyl)-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 100129-35-9 4-(2-chlorophenyl)piperidine 
• 143682-46-6 3-{4-[4-(2-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole 
• 1027023-44-4 1-[4-(2-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-4-(1H-indol-3-yl)-butan-1-one 

Relevant articles and documents

BENZISOXAZOLE COMPOUND

The present invention provides a compound, a salt thereof, or a prodrug thereof as a compound effective for preventing and/or treating fibrosis, the compound being represented by formula (1) (wherein A is an optionally substituted benzene ring; B is optionally substituted aryl or optionally substituted heteroaryl; X is an oxygen atom or a sulfur atom; Y is a nitrogen atom or a carbon atom; ------ of -----Y is a single or double bond when Y is a carbon atom, or ------ of -----Y is a single bond when Y is a nitrogen atom; each R1 independently represents lower alkyl, or two R1s may be bound to each other to form a spiro ring or a crosslinked structure, or two R1s may be bound to each other to form a saturated fused heterocycle together with nitrogen and carbon atoms constituting a ring containing Y; p is 0, 1, or 2; or (R1)p is oxo) .

Synthesis and dopaminergic activity of some 3-(1,2,3,6-tetrahydro-1- pyridylalkyl)indoles. A novel conformational model to explain structure- activity relationships

The synthesis and dopaminergic properties of a novel type of dopamine agonist is described. The number and kind of essential structural elements differ significantly from that of the rigid apomorphine-type dopamine agonists. Using standard molecular modeling techniques, a conformational model is developed proposing a U-shaped conformation which might be energetically preferred through aromatic π-π-interactions between both of the electron rich aromatic structural elements of this class of compounds. Superimposition of conformations of the lead compound 28 with apomorphine yields a novel model explaining the atypical structure-activity relationships found in this class of indolealkylamines.