97530-05-7

Basic information

• Product Name: BOC-TRP-N(OCH3)CH3
• Synonyms: N-ALPHA-T-BOC-L-TRYPTOPHAN N-METHOXY-N-METHYL AMIDE;BOC-L-TRYPTOPHAN N-METHOXY-N-METHYL AMIDE;BOC-TRP-NME(OME);BOC-TRP-N(OCH3)CH3;Nalpha-Boc-L-tryptophan N-methoxy-N-methyl amide;Boc-L-Trp-N(OCH3)CH3;Nα-Boc-L-tryptophanN-methoxy-N-methyl amide99%;tert-butyl N-[(1S)-2-(1H-indol-3-yl)-1-[methoxy(methyl)carbamoyl]ethyl]carbamate
• CAS NO: 97530-05-7
• Molecular Formula: C18H25N3O4
• Molecular Weight: 347.41
• Mol File: 97530-05-7.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Storage Temp.: Store at 0°C
• CAS DataBase Reference: BOC-TRP-N(OCH3)CH3(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-TRP-N(OCH3)CH3(97530-05-7)
• EPA Substance Registry System: BOC-TRP-N(OCH3)CH3(97530-05-7)

Safety Data

• Hazardous Substances Data: 97530-05-7(Hazardous Substances Data)

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 13139-14-5 Boc-Trp-OH 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 73-22-3 L-Tryptophan 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 82689-14-3 N-tert-butyloxycarbonyl-tryptophanal 
• 195325-55-4 {(S)-1-(Methoxy-methyl-carbamoyl)-2-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-ethyl}-carbamic acid tert-butyl ester 
• 1026493-36-6 {(S)-1-Formyl-2-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-ethyl}-carbamic acid tert-butyl ester 
• 195325-72-5 (E)-(4R,5S)-5-tert-Butoxycarbonylamino-4-methanesulfonyloxy-6-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-hex-2-enoic acid methyl ester 
• 195325-70-3 (E)-(4R,5S)-5-tert-Butoxycarbonylamino-4-(tetrahydro-pyran-2-yloxy)-6-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-hex-2-enoic acid methyl ester 
• 1026876-01-6 (3S,4S)-4-Amino-5-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-pent-1-en-3-ol 
• 195325-66-7 (3R,4S)-4-tert-butyloxycarbonylamino-3-hydroxy-5-3'-(N-mesitylene-2-sulfonyl)indolyl-1-pentene 
• 195325-56-5 (3S,4S)-4-tert-butyloxycarbonylamino-3-hydroxy-5-3'-(N-mesitylene-2-sulfonyl)indolyl-1-pentene 
• 195325-71-4 (E)-(4R,5S)-5-tert-Butoxycarbonylamino-4-hydroxy-6-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-hex-2-enoic acid methyl ester 
• 195325-57-6 (3S,4S)-4-tert-butyloxycarbonylamino-3-tetrahydropyranyloxy-5-3'-(N-mesitylene-2-sulfonyl)indolyl-1-pentene 
• 157967-18-5 5-<3,5-bis(trifluoromethyl)phenyl>-2-(N-Bocamino)-1-(3-indolyl)-4-penten-3-one 
• 153828-80-9 5-<3,5-bis(trifluoromethyl)phenyl>-2-(N-Bocamino)-1-(3-indolyl)-3-pentanone 
• 103934-57-2 (tert-butyloxycarbonyl)-L-tryptophyl-ψ(CH2NH)-L-leucine benzyl ester 
• 97530-00-2 (tert-butyloxycarbonyl)-L-tryptophyl-ψ(CH2-NH)-L-leucyl-L-aspartyl-L-phenylalanine amide 

Relevant articles and documents

Isolation, structure elucidation, and total synthesis of tryptopeptins A and B, new TGF-?2 signaling modulators from streptomyces sp.

Two new microbial metabolites, tryptopeptins A (1) and B (2), were isolated from the cultured broth of Streptomyces sp. KUSC-G11, as modulators of the transforming growth factor-?2 (TGF-?2) signaling pathway. Their chemical structures consisting of isoval

Synthesis of chiral branched allylamines through dual photoredox/nickel catalysis

Allylamines are versatile building blocks in the synthesis of various naturally occurring products and pharmaceuticals. In contrast to terminal allylamines, the methods of synthesis of their branched congeners with internal, stereodefined double bonds are less explored. This work describes a new approach for the preparation of allylaminesviacross-coupling of alkyl bromides with simple 3-bromoallylamines by merging the photoredox approach and Ni catalysis. The reaction proceeds under mild conditions, under blue light irradiation, and in the presence of an organic dye, 4CzIPN, as a photocatalyst. The scope of suitable reaction partners is broad, including alkyl bromides bearing reactive functionalities (e.g., esters, nitriles, aldehydes, ketones, epoxides) andN-protected allylamines, as well asN-allylated secondary and tertiary amines and heterocycles. The employment of non-racemic starting materials allows for rapid and easy construction of complex multifunctional allylamine derivatives without the loss of enantiomeric purity.

NOVEL COMPOUNDS

The invention provides compounds of general formula (I) or a pharmaceutically acceptable salt, polymorph or solvate thereof, including all tautomers and stereoisomers thereof, wherein K, W, X; Y and Z are described throughout the description and claims. T