97680-24-5Relevant articles and documents
Synthesis and spectral characterization of N-[2-(4-halophenoxy)-3-(3- chlorophenyl)-3, 4-dihydro-2H-1,3,2-Λ5-benzoxazaphosphinin-2- yliden]-N-substituted amines by the Staudinger reaction
Venkateswarlu,Satyanarayana,Rao, C. V. Nageswara,Naidu, K. Reddy Mohan,Raju, C. Naga
, p. 499 - 504 (2010)
The synthesis of the title compounds was accomplished in four steps. The synthetic route involves the preparation of Schiff's base by reacting salicylaldehyde with m-chloroaniline in EtOH. The Schiff's base was then reduced with NaBH4/MeOH. In the second step, PCl3 was reacted with p-chlorophenol/p-bromophenol in THF in the presence of Et3N to obtain P(III) dichloride derivatives. The reduced Schiff's base and dichloride derivatives were reacted in equimolar quantities in the presence of Et 3N in THF to get the cyclized product. Alkyl azides were prepared by reacting alkyl bromides with sodium azide, and then alkyl azides were treated with the cyclized product to obtain the title compounds. The structure of these novel compounds was elucidated by elemental analysis, IR, 1H, 13C, 31P NMR, and mass spectroscopy.
