97693-15-7Relevant articles and documents
Reactions of Ethyl 4-Chloro-5-pyrimidinecarboxylates with 2-Aminopyridine. Synthesis of 5H-Pyridopyrimidopyrimidin-5-ones and 5H-Pyridopyrimidopyrimidin-5-ones and Rearrangement of the Former to the Latter
Kim, Dong Han
, p. 173 - 176 (2007/10/02)
5H-Pyridopyrimidopyrimidin-5-ones IVa,b and 5H-pyridopyrimidopyrimidin-5-ones Va,b were synthesized from ethyl 4-chloro-5-pyrimidinecarboxylate and 2-aminopyridine.The former compounds were obtained directly upon heating the reactants in ethanol, and the latter were prepared by the fusion of ethyl 4-(2-pyridylamino)-5-pyrimidinecarboxylates obtained as minor products from the above reaction.The angular fused cyclic compounds IVa,b were rearranged to the linear tricycles Vb-f upon heating with amines.