97728-46-6

Basic information

• Product Name: 2-methoxy-1-(2-methylphenyl)ethanone
• Synonyms: 2-methoxy-1-(2-methylphenyl)ethanone
• CAS NO: 97728-46-6
• Molecular Weight: 164.204
• Mol File: 97728-46-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-methoxy-1-(2-methylphenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-1-(2-methylphenyl)ethanone(97728-46-6)
• EPA Substance Registry System: 2-methoxy-1-(2-methylphenyl)ethanone(97728-46-6)

Safety Data

• Hazardous Substances Data: 97728-46-6(Hazardous Substances Data)

Upstream product

• 577-16-2 2-Methylacetophenone 
• 1738-36-9 2-methoxyacetonitrile 
• 95-46-5 2-methylphenyl bromide 
• 67-56-1 methanol 

Relevant articles and documents

Intermolecular C-O Bond Formation with Alkoxyl Radicals: Photoredox-Catalyzed α-Alkoxylation of Carbonyl Compounds

Due to the high reactivity of alkoxyl (RO·) radicals and their propensity to easily undergo β-scission or Hydrogen Atom Transfer (HAT) reactions, intermolecular alkoxylations involving RO· radicals are barely described. We report herein for the first time the efficient intermolecular trapping of alkoxyl radicals by silyl enol ethers. This photoredox-mediated protocol enables the introduction of both structurally simple and more complex alkoxy groups into a wide range of ketones and amides.

Oxidative iodination of carbonyl compounds using ammonium iodide and oxone

A simple, efficient, mild, and regioselective method for oxyiodination of carbonyl compounds has been reported by using NH4I as the source of iodine and Oxone as an oxidant. Various carbonyl compounds such as aralkyl ketones, aliphatic ketones (acyclic and cyclic), and β-keto esters proceeded to the respective α-monoiodinated products in moderate to excellent yields. Unsymmetrical aliphatic ketones reacted smoothly yielding a mixture of 1-iodo and 3-iodo ketones with the predominant formation of 1-iodoproduct.